Worldwide Frequency of Commonly Detected EGFR Mutations

RP Graham, AL Treece, NI Lindeman… - … of pathology & …, 2018 - meridian.allenpress.com
pulmonary adenocarcinoma. Initial data indicated an increased frequency of activating EGFR
mutations … proficiency test for EGFR mutations in lung adenocarcinoma. The accompanying …

Mutation-Specific Antibodies for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer

J Yu, S Kane, J Wu, E Benedettini, D Li, C Reeves… - Clinical Cancer …, 2009 - AACR
mutations. To develop a … of EGFR mutations in NSCLC patients, we generated mutation-specific
rabbit monoclonal antibodies against each of these two most common EGFR mutations

Unique microRNA‐profiles in EGFRmutated lung adenocarcinomas

MM Bjaanæs, AR Halvorsen, S Solberg… - … journal of cancer, 2014 - Wiley Online Library
… and epigenetic alterations in lung cancer. MicroRNAs are … of lung adenocarcinomas and
corresponding normal lung tissue and correlated the expression with clinical data and EGFR- …

Clinical and pathological characteristics of EGFR mutation in operable early-stage lung adenocarcinoma

M Yotsukura, H Yasuda, T Shigenobu, K Kaseda… - Lung Cancer, 2017 - Elsevier
… Among tumors with EGFR mutation, there was no difference in OS (p = 0.140) … EGFR
mutation status was not a prognostic indicator after surgery in early-stage lung adenocarcinoma

… of common and rare EGFR mutations in response to EGFR tyrosine kinase inhibitors and platinum-based chemotherapy in patients with non-small cell lung cancer

O Arrieta, AF Cardona, L Corrales, AD Campos-Parra… - Lung cancer, 2015 - Elsevier
mutations in EGFR is higher in Latin Americans (33.2%) than in individuals of Caucasian
ethnicity [7]. More than 80% of EGFR mutations in lung adenocarcinoma … the L858R mutation in …

EGFR mutations as a prognostic and predictive marker in non-small-cell lung cancer

S Fang, Z Wang - Drug design, development and therapy, 2014 - Taylor & Francis
… only occurred in patients with EGFR mutation in lung cancer. … no correlation between EGFR
mutations and recurrence (HR … P=0.44) in patients with lung adenocarcinoma 20 mm or less. …

[HTML][HTML] Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update

G Bethune, D Bethune, N Ridgway… - Journal of thoracic …, 2010 - ncbi.nlm.nih.gov
… introduction to the role of EGFR in lung cancer and presents some of … lung cancer. Some
studies have reported morphologic characteristics that appear to be associated EGFR mutations

… patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-Lung 2, LUX-Lung 3, and LUX-Lung …

JCH Yang, LV Sequist, SL Geater, CM Tsai… - The lancet …, 2015 - thelancet.com
lung cancer tumours that have EGFR mutations have deletion mutations in exon 19 or the
Leu858Arg point mutation in exon 21, or both (ie, common mutations). However, a subset of …

[HTML][HTML] EGFR mutations and the terminal respiratory unit

Y Yatabe - Cancer and Metastasis Reviews, 2010 - Springer
… to invasive cancer. In this review, … EGFR mutations in lung cancer. I also provide an overview
of the current understanding of the lung adenocarcinoma subset harboring EGFR mutations

[PDF][PDF] Heterogeneous Distribution of EGFR Mutations Is Extremely Rare in Lung Adenocarcinoma

Y Yatabe, K Matsuo, T Mitsudomi - Journal of Clinical Oncology, 2011 - researchgate.net
… However, we failed to detect simultaneous double hot spot mutations in our study of
2,781 patients with lung cancer, among whom 862 carried an EGFR mutation. Most of the …