Residential radon, EGFR mutations and ALK alterations in never-smoking lung cancer cases

A Ruano-Ravina, M Torres-Durán… - European …, 2016 - Eur Respiratory Soc
… if residential radon exposure might cause EGFR mutations or … We obtained residential radon
measurements and clinical … of residential radon between patients with EGFR mutations or …

An overview on the relationship between residential radon and lung cancer: what we know and future research

A Ruano-Ravina, L Martin-Gisbert, K Kelsey… - Clinical and …, 2023 - Springer
… there were no differences in residential radon levels by EGFR mutation status. These results
suggest that radon exposure might be associated with specific EGFR mutations. Finally, a …

Indoor radon exposure increases tumor mutation burden in never-smoker patients with lung adenocarcinoma

SM Lim, JW Choi, MH Hong, D Jung, CY Lee, SY Park… - Lung Cancer, 2019 - Elsevier
… no differences in radon concentrations between patients with and without EGFR mutations.
… in smokers, and we discovered that residential radon exposure was associated with higher …

Radon and lung cancer: current trends and future perspectives

M Riudavets, M Garcia de Herreros, B Besse… - Cancers, 2022 - mdpi.com
residential radon level by subtype of mutations, they were two-fold higher in patients with
EGFR exon 19 deletions compared with patients with EGFR … and EGFR mutations could …

EGFR Somatic Mutations in Lung Tumors: Radon Exposure and Passive Smoking in Former- and Never-Smoking US Women

M Taga, LE Mechanic, N Hagiwara… - … , biomarkers & prevention, 2012 - AACR
… that EGFR mutations may be related to residential radon or passive … radon with lung cancer
risk is thought to be linear (1), so our inverse trend between radon dose and EGFR mutations

Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure

JR Choi, SY Park, OK Noh, YW Koh… - Annals of occupational and …, 2016 - Springer
… frequencies of EGFR mutations in never smokers [10, 15, 16]. … EGFR T790M mutations in
cases not easy to diagnose by other conventional methods and play a role in acquired EGFR-…

Molecular Characteristics of Radon Associated Lung Cancer Highlights MET Alterations

G Gamerith, M Kloppenburg, F Mildner, A Amann… - Cancers, 2022 - mdpi.com
EGFR are the most abundantly studied genes. The largest investigation found that
epidermal growth factor receptor (EGFR)… knowledge about specific mutations or mutation-frequencies …

[HTML][HTML] Novel genetic associations between lung cancer and indoor radon exposure

JR Choi, SB Koh, SY Park, HR Kim, H Lee… - Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… For appropriate tyrosine kinase inhibitor (TKI) treatment, mutations in EGFR must be
determined.30–33 Interestingly, we also highlighted variants in EGFR as common among LCINS …

Indoor radon in EGFR-and BRAF-mutated and ALK-rearranged non–small-cell lung cancer patients

L Mezquita, A Benito, A Ruano-Ravina, J Zamora… - Clinical Lung Cancer, 2019 - Elsevier
radon and molecular alteration in NSCLC. Taga et al 16 in 2012 reported no association
between indoor radon and EGFR mutations … nonsignificant higher radon concentrations for ALK-…

Lung cancer survival in never-smokers and exposure to residential radon: results of the LCRINS study

A Casal-Mourino, A Ruano-Ravina, M Torres-Duran… - Cancer Letters, 2020 - Elsevier
… [20] observed a longer median survival for patients with EGFR mutation than for patients
without any mutations (25.6 and 16.2 months respectively). In their meta-analysis, Liu et al. [27] …