… inhibition of DCLK1 enhances the efficacy of EGFR-TKIs on drug-resistant cells, we hypothesized
that DCLK1 inhibitor and EGFR-TKIs … /GR cells were exposed to either DCLK1-IN-1, …

… In contrast, inhibition of DCLK1 reversed the occurrence of … by DCLK1 is also an important
part of its mediation of EGFR-TKI … that DCLK1 contributes to the activation of EMT in EGFR-TKI-…

… factor receptor,EGFR)上调肝癌细胞 中 DCLK1 mRNA 的表达,Western blot 检测 EGF 是 否
通过EGFR上调肝癌细胞中DCLK1蛋白的表达, 免疫组织化学染色检测 EGFR 和 DCLK1 在 39 例…

… )敏感突变的肺腺 癌患者可以从表皮生长因子受体-酪氨酸激酶抑制 剂(epidermal growth factor
receptor-tyrosine kinase inhibitors, EGFR-TKI)治疗中取得更显著的临床获 益,这为NSCLC患者…

… Due to lack of molecular target therapy (such as EGFR-TKI and ALK inhibition) in lung
squamous cell carcinoma, it is necessary to explore novel biomarkers for developing target …

… DCLK1-activated IL-6/STAT3 pathway by DCLK1 inhibitor … of DCLK1 in TNBC progression,
we supposed that DCLK1 … for the MES subtype and DCLK1 specific inhibitor, DCLK1-IN-1, …

… inhibition (DCLK1-IN-1), and genetic manipulation, we demonstrate that DCLK1 inhibition
… genes related to antigen presentation and EGFR signaling with DCLK1 KO, which could be …

… Numerous studies have implicated the high expression of DCLK1 with poor prognosis
and that the inhibition of DCLK1 via a variety of methods suggests that targeting …

… Before applying antibodies, internal peroxidase activity was inhibited with 3% H 2 O 2 for
5 … Therefore, we created a DCLK1 index to describe a combined assessment of DCLK1 …

… Moreover, the combined use of DCLK1-IN-1 and EGFR-TKIs has been shown to produce a
… of DCLK1 kinase inhibitors in cancer therapy. In summary, DCLK1 kinase inhibitors not only …