EGFR tyrosine kinase inhibitors for EGFR mutation-positive non-small-cell lung cancer: outcomes in Asian populations

ES Kim, B Melosky, K Park, N Yamamoto… - Future …, 2021 - Future Medicine
EGFR tyrosine kinase inhibitors (TKIs) specifically in Asian patients with EGFR mutation-positive
non-small-cell lung cancer. In … - and third-generation EGFR TKIs in Asian populations, …

[HTML][HTML] Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network metaanalysis

Y Zhang, J Sheng, Y Yang, W Fang, S Kang, Y He… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… data of EGFR-TKIs in EGFR-positive NSCLC patients (EGFR … answer which EGFR-TKI is
the best clinical choice for EGFR-… the optimized selection of EGFR-TKIs is different between …

Relationship between PD-L1 expression and outcome in EGFR-mutant lung cancer patients treated with EGFR tyrosine kinase inhibitors

J Liu, M Itchins, A Nagrial, WA Cooper, M De Silva… - Lung Cancer, 2021 - Elsevier
… [4] It remains controversial whether PD-L1 TPS is predictive for EGFR TKI efficacy as … line
1st/2nd EGFR TKI in a metropolitan population with EGFR-mutant lung adenocarcinoma. It also …

Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype

G Metro, R Chiari, S Duranti, A Siggillino, MJ Fischer… - Lung cancer, 2012 - Elsevier
… (EGFR tyrosine kinase inhibitor, EGFR-TKI) in patients with EGFR wild type (WT) advanced
non-small cell lung cancer (… an EGFR WT genotype who were treated with an EGFR-TKI for …

Beyond EGFR TKI in EGFR-mutant non-small cell lung cancer patients: main challenges still to be overcome

J Remon, T Morán, N Reguart, M Majem… - Cancer treatment …, 2014 - Elsevier
… the EGFR TKI until tumor become resistant beyond chemotherapy, stop chemotherapy and
switch to EGFR TKI, introduce the EGFR TKI as … or concurrent EGFR TKI plus chemotherapy. …

[HTML][HTML] … and nivolumab efficacy in EGFR mutation-positive non-small-cell lung cancer based on T790M status after disease progression during EGFR-TKI treatment

K Haratani, H Hayashi, T Tanaka, H Kaneda… - Annals of oncology, 2017 - Elsevier
… (EGFR) mutation-positive non-small-cell lung cancer (NSCLC) patients with different mechanisms
of acquired resistance to EGFR tyrosine kinase inhibitors (TKIs) is … mutation of EGFR. …

[HTML][HTML] The resistance to EGFR-TKIs in non-small cell lung cancer: from molecular mechanisms to clinical application of new therapeutic strategies

C Laface, FM Maselli, AN Santoro, ML Iaia, F Ambrogio… - Pharmaceutics, 2023 - mdpi.com
… receptor (EGFR) gene mutations [3]. Currently, various EGFR tyrosine kinase inhibitors (EGFR-TKIs)
are standard treatment options for patients with activating EGFR gene mutations. …

[HTML][HTML] Drug Tolerance to EGFR Tyrosine Kinase Inhibitors in Lung Cancers with EGFR Mutations

K Suda, T Mitsudomi - Cells, 2021 - mdpi.com
… to EGFR TKIs, the vast majority of EGFR-mutated lung cancer cells are killed within a few days
upon exposure to a clinically relevant concentration of an EGFR TKI, … of an EGFR TKI [21]. …

[HTML][HTML] Third generation EGFR TKIs: current data and future directions

CS Tan, NB Kumarakulasinghe, YQ Huang, YLE Ang… - Molecular cancer, 2018 - Springer
… growth factor receptor (EGFR) T790 M mutation-positive non-small cell lung cancer (NSCLC),
as detected by an US FDA-approved test, whose disease has progressed on or after …

Risk of interstitial lung disease associated with EGFR-TKIs in advanced non-small-cell lung cancer: a meta-analysis of 24 phase III clinical trials

WX Qi, YJ Sun, Z Shen, Y Yao - Journal of chemotherapy, 2015 - Taylor & Francis
… and many other types of cancer. Currently, two reversible EGFR tyrosine kinase inhibitors
(EGFR-TKIs), gefitinib and erlotinib, and one irreversible EGFR, human epidermal growth …