… growth factor receptor (EGFR) mutations, the EGFR tyrosine kinase inhibitors (EGFR-TKIs,
eg.… Resistance to EGFR-TKIs is inevitable due to various mechanisms, such as the secondary …

… mutations in EGFR are associated with dramatic and sustained responses to anti-EGFR
treatments. This review summarizes the clinical development of EGFR tyrosine kinase inhibitors, …

… of the EGFR tyrosine kinase results in inhibition of tumor cell … anilinoquinazoline capable of
inhibiting EGFR tyrosine kinase in vitro… the antitumor effect of EGFR tyrosine kinase inhibitors. …

… EGFR mutations where an EGFR TKI–… tyrosine kinase domain of EGFR. In this study, we
report the frequency of and responses to EGFR TKIs of our center’s cohort of compound EGFR-…

… are the EGFR tyrosine kinase inhibitors (EGFR-TKIs), of which … of EGFR expression.
Furthermore, in addition to an effect on … regarding the MOA of EGFR tyrosine kinase inhibitors …

… -tyrosine kinase inhibitor was first approved for the treatment of advanced lung cancer in 2002.
Epidermal growth factor receptor-tyrosine kinase inhibitor plays … -tyrosine kinase inhibitor …

… growth factor receptor tyrosine kinase inhibitors erlotinib and … do not respond to these tyrosine
kinase inhibitors, and those … next-generation tyrosine kinase inhibitors are being developed…

… (EGFR) frequently derive significant clinical and radiographic benefits from treatment with
EGFR tyrosine kinase inhibitors (TKIs). As such, prospective identification of EGFR mutations …

… therapy such as tyrosine kinase inhibitor for Epidermal Growth Factor Receptor (EGFR), …
rate of resistance among individuals with mutant EGFR. Therefore, the development of new …

… (EGFR) are particularly sensitive to tyrosine kinase inhibitors (… evaluate the benefit of EGFR
TKIs in EGFR-mutated NSCLCs… therapy in 1260 patients with EGFR-mutated NSCLCs who …