Impact of comorbidities on clinical outcomes in non-small cell lung cancer patients who are elderly and/or have poor performance status

J Ngeow, SS Leong, F Gao, CK Toh, WT Lim… - Critical reviews in …, 2010 - Elsevier
… in patients who have good performance status … to patients who are elderly or with poor
performance status. An important randomized study in elderly NSCLC patients done by the Elderly

Meeting the chemotherapy needs of elderly and poor performance status patients with NSCLC

C Gridelli, J Hainsworth - Lung cancer, 2002 - Elsevier
… Increasing interest in designing chemotherapy suitable for use in the elderly and in poor
performance status (PS) patients has led to clinical trials in advanced non-small cell lung cancer …

Ongoing challenges of using immunotherapy in special populations: Poor performance status patients, elderly patients, and people living with HIV

V Gounant, A Lavolé, E Quoix - Lung Cancer, 2020 - Elsevier
patients. However, most clinical trials on ICIs conducted so far have either excluded patients
with poor performance status (… only a minor proportion of elderly patients despite the lack of …

Role of stereotactic body radiotherapy in the treatment of elderly and poor performance status patients with pancreatic cancer

LM Rosati, JM Herman - Journal of oncology practice, 2017 - ascopubs.org
… in patients who are elderly or have poor performance status is … unique cohort of patients is
< 6 months, and most patients are only … survival in elderly or poor performance status patients. …

[HTML][HTML] A phase II study of cetuximab and radiation in elderly and/or poor performance status patients with locally advanced non-small-cell lung cancer (N0422)

A Jatoi, SE Schild, N Foster, GT Henning, KJ Dornfeld… - Annals of oncology, 2010 - Elsevier
… Nonetheless, the results of the current trial, coupled with earlier results from the RTOG, indicate
that … is warranted in elderly and/or poor performance status patients with this malignancy. …

[HTML][HTML] A randomized phase II trial of two schedules of docetaxel in elderly or poor performance status patients with advanced non-small cell lung cancer

R Lilenbaum, M Rubin, J Samuel, L Boros… - Journal of Thoracic …, 2007 - Elsevier
… the first-line treatment of elderly and performance status (PS) 2 patients with advanced non-…
Our results help clarify important differences between elderly and PS 2 patients and provide …

Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial

JG Pérez-Larraya, F Ducray, O Chinot… - Journal of clinical …, 2011 - ascopubs.org
… The management of glioblastoma multiforme (GBM) in elderly patients with poor performance
status is not well established. A trial evaluating the efficacy and safety of temozolomide …

Weekly docetaxel versus docetaxel/gemcitabine in the treatment of elderly or poor performance status patients with advanced nonsmall cell lung cancer: a …

JD Hainsworth, DR Spigel, C Farley, DL Shipley… - Cancer, 2007 - Wiley Online Library
… and younger patients derived similar benefit from treatment … 3 trial designed specifically for
elderly patients, single-agent … treatment for elderly and poor performance status patients, we …

The impact of performance status and comorbidities on the short-term prognosis of very elderly patients admitted to the ICU

FG Zampieri, F Colombari - BMC anesthesiology, 2014 - Springer
… comorbidities and performance status, on short-term outcomes in the very elderly is largely
… in critically ill patients ≥80 years old, emphasizing performance status and comorbidities, …

[HTML][HTML] Phase II trial of single-agent oral vinorelbine in elderly (≥ 70 years) patients with advanced non-small-cell lung cancer and poor performance status

A Camerini, C Valsuani, F Mazzoni, O Siclari… - Annals of …, 2010 - Elsevier
… , consequently, our results could be transferred to similar patients in clinical practice. Our
results enforce the role of CGA in elderly and/or low-PS lung cancer patients and we strongly …