Efficacy and safety of apixaban compared with aspirin in the elderly: a subgroup analysis from the AVERROES trial
KH Ng, O Shestakovska, SJ Connolly… - Age and …, 2016 - academic.oup.com
… We report the effects of apixaban versus acetylsalicylic acid (ASA) in older patients (≥75
years … , it difficult to justify the use of aspirin in elderly patients with AF, if apixaban is available. …
years … , it difficult to justify the use of aspirin in elderly patients with AF, if apixaban is available. …
Anticoagulants for stroke prevention in atrial fibrillation in elderly patients
A Schäfer, U Flierl, D Berliner, J Bauersachs - Cardiovascular drugs and …, 2020 - Springer
… In summary, it seems reasonable to use NOACs for elderly patients with AF instead … elderly
patients compared with VKA on apixaban followed by edoxaban, whereas in elderly patients, …
patients compared with VKA on apixaban followed by edoxaban, whereas in elderly patients, …
Effect of apixaban versus warfarin use on health care resource utilization and costs among elderly patients with nonvalvular atrial fibrillation
S Deitelzweig, X Luo, K Gupta, J Trocio… - Journal of Managed …, 2017 - jmcp.org
… versus warfarin on HCRU and costs among elderly NVAF patients. The results of the study
show that elderly NVAF patients who initiated apixaban significantly differed in many patient …
show that elderly NVAF patients who initiated apixaban significantly differed in many patient …
Clinical implications of assessment of apixaban levels in elderly atrial fibrillation patients: J-ELD AF registry sub-cohort analysis
S Suzuki, T Yamashita, M Akao, K Okumura… - European Journal of …, 2020 - Springer
… dose (in the present study, ≥86 ng/mL) could be a tool for identifying those with a high risk
of bleeding among elderly patients with AF, although a high Api-AXA value itself does not …
of bleeding among elderly patients with AF, although a high Api-AXA value itself does not …
Effects of age and sex on the single-dose pharmacokinetics and pharmacodynamics of apixaban
CE Frost, Y Song, A Shenker, J Wang, YC Barrett… - Clinical …, 2015 - Springer
… The apixaban CL R tended to be lower in elderly subjects (0.45 L/h) than in young subjects
(0.63 L/h) and lower in female subjects (0.46 L/h) than in male subjects (0.62 L/h); these …
(0.63 L/h) and lower in female subjects (0.46 L/h) than in male subjects (0.62 L/h); these …
A multicenter prospective cohort study to investigate the effectiveness and safety of apixaban in Japanese elderly atrial fibrillation patients (J‐ELD AF Registry)
K Okumura, T Yamashita, S Suzuki, M Akao… - Clinical …, 2020 - Wiley Online Library
… of the on-label reduced dose apixaban in >1700 elderly AF patients, supporting the conclusions
shown in the ARISTOTLE subanalysis for the elderly patients.14 Since underdosing of …
shown in the ARISTOTLE subanalysis for the elderly patients.14 Since underdosing of …
[PDF][PDF] Efficacy and safety of oral anticoagulation in elderly patients with atrial fibrillation.
I Cavallari, G Patti - Anatolian Journal of Cardiology/Anadolu …, 2018 - jag.journalagent.com
… However, data from phase III clinical trials on atrial fibrillation overall indicate that apixaban
and edoxaban in elderly patients are associated with the highest reduction of extracranial …
and edoxaban in elderly patients are associated with the highest reduction of extracranial …
Effectiveness and safety of oral anticoagulants in elderly patients with atrial fibrillation
OCW Rutherford, C Jonasson, W Ghanima… - Heart, 2022 - heart.bmj.com
… in elderly patients with atrial fibrillation (AF) in a real-world population. Methods We identified
all anticoagulant-naive initiators of warfarin, dabigatran, rivaroxaban and apixaban for the …
all anticoagulant-naive initiators of warfarin, dabigatran, rivaroxaban and apixaban for the …
[HTML][HTML] Efficacy and safety of novel anticoagulants in the elderly
N Karamichalakis, S Georgopoulos… - Journal of geriatric …, 2016 - ncbi.nlm.nih.gov
… studies with elderly participants have shown that apixaban is … safety of apixaban is consistent
among various groups of patients, … Elderly patients with AF and VTE are at elevated risk of …
among various groups of patients, … Elderly patients with AF and VTE are at elevated risk of …
Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-analysis
M Grymonprez, S Steurbaut, TL De Backer… - Frontiers in …, 2020 - frontiersin.org
… was observed in older AF patients, as opposed to lower risks for apixaban and edoxaban. …
of NOACs versus VKAs in elderly atrial fibrillation patients ≥75 years old. Api 5/2.5, …
of NOACs versus VKAs in elderly atrial fibrillation patients ≥75 years old. Api 5/2.5, …
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