A phase II trial of erlotinib monotherapy for pretreated elderly patients with advanced EGFR wild-type non-small cell lung cancer

H Minemura, H Yokouchi, K Azuma, K Hirai… - BMC Research …, 2015 - Springer
patients with disease progression after cytotoxic chemotherapy might benefit from erlotinib
monotherapy. … - or third-line erlotinib monotherapy for elderly patients with EGFR-wt advanced …

Efficacy and safety of first-line erlotinib in elderly patients with advanced non-small cell lung cancer

O Merimsky, CK Cheng, JSK Au… - Oncology …, 2012 - spandidos-publications.com
… of erlotinib, designed to allow access to erlotinib monotherapyolder patients (≥70 years)
who participated; this report describes outcomes among elderly patients who received erlotinib

Erlotinib as second‑or third‑line treatment in elderly patients with advanced non‑small cell lung cancer: Keio Lung Oncology Group Study 001 (KLOG001)

M Miyawaki, K Naoki, S Yoda… - Molecular and …, 2017 - spandidos-publications.com
… second- or third-line erlotinib treatment in elderly patients with NSCLC. The primary endpoint
… received platinum-based combination chemotherapy and 3 patients received monotherapy

Clinical effect of erlotinib as first-line treatment for Asian elderly patients with advanced non-small-cell lung cancer

XH Xu, J Su, XY Fu, F Xue, Q Huang, DJ Li… - Cancer chemotherapy …, 2011 - Springer
… II study of erlotinib as first-line treatment in Asian elderly patients with … patients, erlotinib
monotherapy was effective and well tolerated as a first-line treatment in Asian elderly patients

… II trial of sequential erlotinib and gemcitabine compared with gemcitabine monotherapy as first‐line therapy in elderly or ECOG PS two patients with advanced NSCLC

M Michael, SC White, E Abdi, L Nott… - Asia‐Pacific Journal …, 2015 - Wiley Online Library
… The potential beneficial interaction between erlotinib and … of sequential erlotinib and
gemcitabine versus gemcitabine monotherapy as first-line therapy in elderly or ECOG PS-2 patients

[HTML][HTML] Efficacy and safety of erlotinib in elderly patients in the phase IV POLARSTAR surveillance study of Japanese patients with non-small-cell lung cancer

H Yoshioka, K Komuta, F Imamura, S Kudoh, A Seki… - Lung cancer, 2014 - Elsevier
… with pretreated NSCLC were randomized to four separate phase II targeted therapies
including erlotinib monotherapy, clinical outcomes of patients aged >65 years were comparable …

Activity and safety of erlotinib as second-and third-line treatment in elderly patients with advanced non-small cell lung cancer: a phase II trial

D Rossi, D Dennetta, M Ugolini, V Catalano… - Targeted …, 2010 - Springer
… population derived especially from two Italian phase III trials: in the ELVIS study [4], a
monotherapy with vinorelbine demonstrated a significant survival benefit over best supportive care …

Treating non-small-cell lung cancer first line with erlotinib monotherapy in elderly patients: discussion of a case series

M Reck - Oncology Research and Treatment, 2007 - karger.com
Erlotinib was effective and well tolerated as a first-line treatment in the elderly patients with
… it demonstrates that erlotinib can be a valid treatment option for patients who are unsuitable …

[HTML][HTML] … of a randomized phase II trial of first-line therapy with gemcitabine, erlotinib, or the combination in elderly patients (age 70 years or older) with stage IIIB/IV …

TE Stinchcombe, J Roder, AH Peterman… - Journal of Thoracic …, 2013 - Elsevier
monotherapy arm, nine of the patients classified as Good and three classified as Poor
went on to receive erlotinib therapy as a second-line therapy. Outcomes on the erlotinib and …

Phase II study of erlotinib in elderly patients with non-small cell lung cancer harboring epidermal growth factor receptor mutations

Y Inoue, N Inui, K Asada, M Karayama… - Cancer chemotherapy …, 2015 - Springer
… , no prospective erlotinib data focusing on elderly patients with EGFR mutations are available
and the present study demonstrates the benefit of erlotinib for those patients for the first …