First-line treatment strategies for elderly patients with metastatic colorectal cancer

HJ Meulenbeld, GJ Creemers - Drugs & aging, 2007 - Springer
… of elderly patients into these trials. Randomised clinical trials focusing on first-line treatment
regimens of irinotecan in elderly patients … with use of irinotecan in elderly patients is advised. …

First-line treatment of newly diagnosed elderly patients with chronic myeloid leukemia: current and emerging strategies

G Gugliotta, F Castagnetti, M Apolinari, S Pirondi… - Drugs, 2014 - Springer
… in most Western countries for the first-line treatment of CML. These drugs differ in … of elderly
CML patients. We reviewed the impact of age on the first-line treatment of CP CML patients in …

[HTML][HTML] First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)—a systematic review and individual patient data …

B Kasenda, AJM Ferreri, E Marturano, D Forst… - Annals of …, 2015 - Elsevier
… and individual patient data meta-analysis to comprehensively investigate prognosis and
treatment strategies for elderly patients with newly diagnosed PCNSL. patients and methods …

Are β-blockers efficacious as first-line therapy for hypertension in the elderly?: a systematic review

FH Messerli, E Grossman, U Goldbourt - Jama, 1998 - jamanetwork.com
… as first-line agents. We included only trials that evaluated effects of … treatment on morbidity
or mortality in elderly persons with hypertension (≥60 years). Trials that examined therapy of …

Elderly and very elderly patients with hepatocellular carcinoma. Strategy for a first line treatment

S Brozzetti, M Bezzi, GM De Sanctis… - Annali Italiani di …, 2014 - annaliitalianidichirurgia.it
… candidates for ablation because this procedure enables the treatmentfirst line treatments
in a surgical setting developed to minimize procedure -related risks in different elderly patients

Therapeutic strategies in elderly and very elderly patients

P Soubeyran, BH de Figueiredo, I Soubeyran… - Best Practice & …, 2012 - Elsevier
… management of the elderly patient. Still, other … elderly with aggressive lymphomas. This
includes molecular biology of aggressive lymphomas which may lead to new targeted treatments

Elderly onset rheumatoid arthritis: differential diagnosis and choice of first-line and subsequent therapy

JI Villa-Blanco, J Calvo-Alen - Drugs & aging, 2009 - Springer
… associated with methotrexate treatment in elderly patients,[72,73] … treatment appears
safe and effective in EORA patients and … the major risks associated with this treatment.[69,71–78] …

A randomised multicentre phase II trial of capecitabine vs S-1 as first-line treatment in elderly patients with metastatic or recurrent unresectable gastric cancer

JL Lee, YK Kang, HJ Kang, KH Lee, DY Zang… - British journal of …, 2008 - nature.com
… tolerable as first-line treatment for elderly patients with AGC. … Elderly patients may be the
best target population for this … good and safe first-line treatment option for this patient group and …

Phase II study of S-1 as first-line treatment for elderly patients over 75 years of age with advanced gastric cancer: the Tokyo Cooperative Oncology Group study

W Koizumi, T Akiya, A Sato, T Sakuyama… - Cancer chemotherapy …, 2010 - Springer
… Since the possible usefulness of this therapy in elderly patients with gastric cancer was
thus suggested, this study was designed to investigate this issue. However, since CDHP, a …

First-line gefitinib treatment in elderly patients (aged ≥75 years) with non-small cell lung cancer harboring EGFR mutations

T Kuwako, H Imai, T Masuda, Y Miura, K Seki… - Cancer chemotherapy …, 2015 - Springer
first-line gefitinib therapy in elderly patients with EGFR-mutated NSCLC results in prolonged
PFS, compared with that reported in younger patients. … first-line treatment for elderly patients. …