Management of glioblastoma multiforme in elderly patients: a review of the literature

SH Halani, R Babu, DC Adamson - World Neurosurgery, 2017 - Elsevier
… survival in this often-forgotten patient population. This review aims to highlight the current
literature on surgical and medical management of GBM in elderly patients, including our own …

Management of elderly patients with glioblastoma-multiforme—a systematic review

A Almadani, S Dixit, C Rowland-Hill… - The British Journal of …, 2018 - academic.oup.com
The management of elderly patients with glioblastoma-multiforme (GBM) remains poorly
defined with many experts in the past advocating best supportive care, in view of limited …

Treatment of elderly patients with glioblastoma: a systematic evidence-based analysis

OJ Zarnett, A Sahgal, J Gosio, J Perry… - JAMA …, 2015 - jamanetwork.com
patients diagnosed as having glioblastoma multiforme (GBM) remain poor. Survival is further
limited in elderly patients, … approach for elderly patients (aged >65 years) with GBM remains …

Treatment results and outcome in elderly patients with glioblastoma multiforme–a retrospective single institution analysis

M Hoffermann, L Bruckmann, KM Ali, M Asslaber… - Clinical Neurology and …, 2015 - Elsevier
Objective Although glioblastoma multiforme is more common in patients older than 65 years,
the elderly population is often excluded from clinical studies. Decision making in this …

Treatment of glioblastoma multiforme in elderly patients. Clinico-therapeutic remarks in 22 patients older than 80 years

M Piccirilli, S Bistazzoni, FM Gagliardi… - Tumori …, 2006 - journals.sagepub.com
elderly has a poor response to multimodality treatmenr'". Elderly patients affected by glioblastoma
multiforme … from therapeutic trials specific for younger patients. Otherwise, we have to …

Short course of radiation therapy in elderly patients with glioblastoma multiforme

A Idbaih, S Taillibert, JM Simon, D Psimaras… - Cancer …, 2008 - Elsevier
elderly patients suffering from glioblastoma multiforme (GBM) … GBM and give promising
results [11], [13], [16], [18]. These … constitute also a hope in elderly patients suffering from GBM. …

Survival outcomes of elderly patients with glioblastoma multiforme in their 75th year or older treated with adjuvant therapy

G Harris, D Jayamanne, H Wheeler, C Gzell… - International Journal of …, 2017 - Elsevier
… underrepresent elderly patients aged >75 years with GBM. Despite elderly patients having a
… of survival benefits with IMRT for selected patients that can be further extended with addition …

Outcomes and patterns of care in elderly patients with glioblastoma multiforme

RS Nunna, SI Khalid, S Patel, A Sethi, M Behbahani… - World neurosurgery, 2021 - Elsevier
… in elderly patients remains unclear. This study seeks to investigate the effect of patient
Among 104,456 patients with GBM identified, elderly patients were less likely to receive …

Glioblastoma multiforme in the elderly: a therapeutic challenge

A Mangiola, G Maira, P De Bonis, M Porso… - Journal of neuro …, 2006 - Springer
… Introduction: Elderly patients with glioblastoma multiforme (GBM… The average survival in
elderly patients is 4–8 months. The … terms of survival in an elderly population affected with GBM. …

Glioblastoma multiforme of the elderly: the prognostic effect of resection on survival

C Ewelt, M Goeppert, M Rapp, HJ Steiger… - Journal of neuro …, 2011 - Springer
… We therefore addressed the issue of whether elderly patients (>65years) could also benefit
from cytoreductive surgery (CS) and adjuvant treatment using alkylating chemotherapy. One-…