[HTML][HTML] Elevated risk of type 2 diabetes for development of Alzheimer disease: a key role for oxidative stress in brain

DA Butterfield, F Di Domenico, E Barone - … BBA)-Molecular Basis of Disease, 2014 - Elsevier
Alzheimer disease (AD) is the most common form of dementia among the elderly and is
characterized by progressive loss of memory and cognition. Epidemiological data show that the …

Polygenic risk of Alzheimer disease is associated with early-and late-life processes

…, Alzheimer's Disease Neuroimaging Initiative… - Neurology, 2016 - AAN Enterprises
… This analysis revealed a similar association such that elevated PGRS was associated with
greater (eg, more AD-like) levels of florbetapir Aβ (p = 0.03, figure 3B). Across both analyses, …

Elevated serum pesticide levels and risk for Alzheimer disease

JR Richardson, A Roy, SL Shalat, RT Von Stein… - JAMA …, 2014 - jamanetwork.com
Importance The causes of late-onset Alzheimer disease (AD) are not yet understood but
likely include a combination of genetic, environmental, and lifestyle factors. Limited …

Relative risk for Alzheimer disease based on complete family history

LA Cannon-Albright, NL Foster, K Schliep… - Neurology, 2019 - AAN Enterprises
… Among the constellations considered, a family history on the mother's side gave significantly
elevated risk while the equivalent family history on the father's side did not (eg, ≥1 mother's …

Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
… However, data from observational studies exploring the association between elevated
across cohorts suggesting that elevated blood pressure in mid-life does increase the risk of later-…

Apolipoprotein E ε4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

M Kivipelto, EL Helkala, MP Laakso… - Annals of internal …, 2002 - acpjournals.org
… , is the most important genetic risk factor for Alzheimer disease. Elevated midlife values for
total … The risk for Alzheimer disease from treatable factors—elevated total cholesterol level and …

Alzheimer disease

JL Cummings, G Cole - Jama, 2002 - jamanetwork.com
… Other risk factors implicated in a variety of studies include head injury, low serum levels of
folate and vitamin B12, elevated plasma and total homocysteine levels, family history of AD or …

An association of elevated serum gonadotropin concentrations and Alzheimer disease?

Bowen, Isley, Atkinson - Journal of neuroendocrinology, 2000 - Wiley Online Library
… hypothesis for the mechanism of Alzheimer disease. This paper suggests an association of
elevated serum gonadotropin concentrations with Alzheimer disease. A potential mechanism …

Inflammatory markers and the risk of Alzheimer disease: the Framingham Study

ZS Tan, AS Beiser, RS Vasan, R Roubenoff… - Neurology, 2007 - AAN Enterprises
… ; persons with elevated serum levels of CRP and IL-6 were at greater risk of dying during …
), whereas elevated PBMC production of cytokines was not associated with a greater risk of …

Modifiable risk factors in Alzheimer disease and related dementias: a review

R Litke, LC Garcharna, S Jiwani, J Neugroschl - Clinical therapeutics, 2021 - Elsevier
… From 2009 to 2011, 1260 adults in Finland 60 to 77 years of age, with an elevated risk of
dementia (as defined by a Cardiovascular Risk Factors, Aging, and Dementia Dementia Risk