… as downstream products in tissues undergoing DNA demethylation. Despite confirming the
… -stage embryos. This mechanism may offer some explanation for the observed demethylation …

… the developing embryo must negotiate lineage defining and developmental commitment …
In this chapter, the mechanistic possibilities for DNA demethylation will be described in the …

… in the arrest of mouse embryonic development around E9.5, when the embryo is in the process
of … undergo global DNA demethylation during preimplantation development. As a result, …

… of this transcription-related function of TDG required for proper embryonic development. …
DNA demethylation in a manner similar to that in zebrafish embryos, where demethylation is …

… pronucleus in early preimplantation development. In this study, we have investigated and
compared the dynamics of DNA demethylation in preimplantation mouse and rat embryos by …

… Jost, JP: Nuclear extracts of chicken embryos promote an active demethylation of DNA by …
Jost, JP and Jost, YC: Transient DNA demethylation in differentiating mouse myoblasts …

… genomic imprinting in the mammalian embryo (21). This large enzyme (1,620 amino acids)
is targeted to replication foci consistent with the rapid remethylation of DNA in somatic cells (…

… the loss of DNA methylation results from an active targeted process of DNA demethylation. …
errors that may arise during early embryonic development in humans, especially those that …

… Imprinting takes place in the endosperm, a tissue that supports embryo growth during seed
development and seedling germination. Active DNA demethylation has been implicated in …

… DNA demethylation in IVF embryos, we next asked if the gene expression level of Tet family
members was inhibited in IVF preimplantation embryos. … inhibited in IVF embryos at the two- …