… syndrome type 3, sick sinus syndrome, and a variable degree of conduction disturbance (first
degree to complete AV block) known as overlap syndrome… and long-QT-syndrome type 3, a …

… mutation in SCN5A results in Brugada syndrome (BrS), … SCN5A also results in Long QT
syndrome type 3 (LQTS3), leading … in embryonic and adult hearts. SCN3B is highly expressed in …

… Brugada syndrome (BrS) was first described in 1992 as an aberrant pattern of ST segment
… Genetic Diagnosis (PGD) of embryos, overlapping syndromes, risk stratification, familial …

… A Tbx2-positive and Gja1-negative myocardial gene programme, and the slow-conducting
phenotype of the embryonic outflow tract myocardium, was shown to be maintained in the …

… The left panel shows a clear Type 1 ECG, which is diagnostic of the Brugada syndrome. A
saddleback ST-segment elevation (Type 2) is observed on February 7,1999. The ST segment …

… In the following years, it was to become known as “Brugada syndrome” (2). With an estimated
prevalence of 1 to 5 in 10 000, Brugada syndrome (BrS) is one of the commoner forms of …

… Brugada syndrome. The aim of this study is to review the available literature on the Brugada
syndrome … of the mechanism of the Brugada syndrome. This unifying hypothesis should be …

… Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada
syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.…

… of electrical instability in Brugada syndrome is still debated. … clinical phenotype of Brugada
syndrome and normal cardiac … in all 18 patients with Brugada syndrome. Mutations in the …

… substrate of the ECG manifestations in Brugada syndrome to the RVOT. 2 Demonstration of
… supporting the RVOT as the anatomic substrate of Brugada syndrome. 2, 5–8 Interestingly, …