Upholding a role for EMT in pancreatic cancer metastasis
… network that defines and orchestrates EMT in pancreatic carcinomas, we believe that the …
versions of the EMT program and therefore to completely suppress activation of EMT. Hence…
versions of the EMT program and therefore to completely suppress activation of EMT. Hence…
EMT and treatment resistance in pancreatic cancer
… we summarize the role of EMT in the context of drug resistance and metastasis in PC, with a
… However, the role of the microbiome in EMT induction in pancreatic cancer cells is plausible …
… However, the role of the microbiome in EMT induction in pancreatic cancer cells is plausible …
[HTML][HTML] Pancreatic cancer stem cells and EMT in drug resistance and metastasis
FH Sarkar, Y Li, Z Wang, D Kong - Minerva chirurgica, 2009 - ncbi.nlm.nih.gov
… EMT has been shown to be important on conferring drug resistance characteristics to cancer
… We have reported that EMT in pancreatic cancer influences the sensitivity of cancer cells to …
… We have reported that EMT in pancreatic cancer influences the sensitivity of cancer cells to …
[HTML][HTML] The role of EMT in pancreatic cancer progression
Q Wu, L Miele, FH Sarkar, Z Wang - Pancreatic disorders & therapy, 2012 - ncbi.nlm.nih.gov
… In summary, EMT has been found to play critical roles in the control of tumor invasion,
metastasis and drug resistance in PCa. Several factors, cytokines and cellular signaling pathways …
metastasis and drug resistance in PCa. Several factors, cytokines and cellular signaling pathways …
The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer
AM Krebs, J Mitschke, M Lasierra Losada… - Nature cell …, 2017 - nature.com
… role for the EMT-TF Zeb1 in the in vivo progression of pancreatic cancer from early precursor
lesions towards metastasis. Genetic depletion of Zeb1 in the pancreas reduces formation of …
lesions towards metastasis. Genetic depletion of Zeb1 in the pancreas reduces formation of …
[HTML][HTML] Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
MV Recouvreux, MR Moldenhauer… - Journal of Experimental …, 2020 - rupress.org
… EMT) in pancreatic ductal adenocarcinoma (PDAC) cells. Mechanistically, we demonstrate
that glutamine deficiency regulates EMT through the up-regulation of the EMT … –induced EMT, …
that glutamine deficiency regulates EMT through the up-regulation of the EMT … –induced EMT, …
[HTML][HTML] EMT and dissemination precede pancreatic tumor formation
… breast cancer, have given rise to two major metastasis paradigms. The classical model treats
metastasis … serve as independent predictors of mortality in patients with pancreatic cancer ( …
metastasis … serve as independent predictors of mortality in patients with pancreatic cancer ( …
The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer
P Zhou, B Li, F Liu, M Zhang, Q Wang, Y Liu, Y Yao… - Molecular cancer, 2017 - Springer
… role of EMT and PCSCs in tumor progression, metastasis and … in treatment resistance of
pancreatic cancer. These findings … controlling EMT and cancer stem cells in pancreatic cancer …
pancreatic cancer. These findings … controlling EMT and cancer stem cells in pancreatic cancer …
Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance
Z Guo, M Ashrafizadeh, W Zhang, R Zou… - Cancer and metastasis …, 2024 - Springer
… of cancer cells has been related to the development of drug resistance. Metastasis of pancreatic
cancer (PC… The stimulation of EMT in PC cells occurs as a result of changes in molecular …
cancer (PC… The stimulation of EMT in PC cells occurs as a result of changes in molecular …
Epithelial‐mesenchymal transition in pancreatic cancer: a review
S Wang, S Huang, YL Sun - BioMed research international, 2017 - Wiley Online Library
… the roles of EMT in the dissemination and metastasis of pancreatic … EMT during the metastatic
process of pancreatic cancer. Circulating tumor cells (CTCs) or circulating pancreatic cells (…
process of pancreatic cancer. Circulating tumor cells (CTCs) or circulating pancreatic cells (…
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