Enantiomeric determination of drugs in pharmaceutical formulations and biological samples by electrokinetic chromatography

N Casado, J Valimaña-Traverso… - Critical reviews in …, 2020 - Taylor & Francis
… of the low concentration at which drug enantiomers can be found in biological samples
and due to their complex matrix, a sample preparation and preconcentration technique was …

Determination of enantiomeric composition of ibuprofen in pharmaceutical formulations by partial least-squares regression of strongly overlapped chromatographic …

JO Grisales, JA Arancibia, CB Castells… - … of Chromatography B, 2012 - Elsevier
… R-enantiomer can be detected in these samples in a proportion of 0.5:500, ie, about 1:1000,
which means that the ratio of enantiomers … for the R-enantiomer detected in these samples. …

Enantiomeric composition of abused amine drugs: chromatographic methods of analysis and data interpretation

JT Liu, RH Liu - Journal of Biochemical and Biophysical Methods, 2002 - Elsevier
enantiomeric compositions of these compounds and their metabolites; (b) enantiomeric
composition … (c) interpretative value of the observed enantiomeric composition. Thus, the focus of …

Determination of the enantiomeric composition of salsolinol in biological samples by high-performance liquid chromatography with electrochemical detection

E Pianezzola, V Bellotti, E Fontana, E Moro… - … of Chromatography B …, 1989 - Elsevier
… The enantiomers of … the enantiomeric composition of salsolinol in human urine. The sensitivity
and specificity to the assay also permit the determination of the enantiomeric composition

Enantiomer fractions are preferred to enantiomer ratios for describing chiral signatures in environmental analysis

T Harner, K Wiberg, R Norstrom - Environmental science & …, 2000 - ACS Publications
… of enantiomeric (chiral) signatures for environmental samples. In this paper, we argue for the
adoption of the enantiomer … The enantiomer fraction is superior because it provides a more …

Enantiomeric determination of chiral persistent organic pollutants and their metabolites

E Eljarrat, P Guerra, D Barceló - TrAC Trends in Analytical Chemistry, 2008 - Elsevier
… , but frequently undergo alterations in enantiomeric composition as soon as they are … ,
since enantiomers of chiral compounds often exhibit differences in biological activity, and …

Chiral recognition and determination of enantiomeric excess by mass spectrometry: A review

X Yu, ZP Yao - Analytica chimica acta, 2017 - Elsevier
… Therefore, chiral recognition and quantitative determination of individual enantiomers are …
of the enantiomeric composition, which is usually described in terms of enantiomeric excess (…

Simultaneous determination of concentration and enantiomeric composition in fluorescent sensing

L Pu - Accounts of chemical research, 2017 - ACS Publications
enantiomeric compositions. Figure 2a shows that the fluorescence intensity of the sensor at λ
1 is only slightly influenced by the enantiomeric composition … and enantiomeric composition

Analysis of enantiomers in products of food interest

C Fanali, G D'Orazio, A Gentili, S Fanali - Molecules, 2019 - mdpi.com
… In this review, general principles of enantiomers separation utilizing chromatographic
techniques and the most applied chiral stationary phases (CSPs) are reported and discussed. In …

Electrophoretic separation of tryptophan enantiomers in biological samples

S Zhao, YM Liu - Electrophoresis, 2001 - Wiley Online Library
… of amino acid enantiomers present in biological samples. … for D-amino acid analysis in
biological samples [11]. However, … the separation of amino acid enantiomers have been reported […