… oocyte maturation in meioti- successive periods of meiotic arrest and resumption durcally
arrested cumulus cell-enclosed oocytes. Oo-cytes ing the ontogeny of the oocyte. The …

… In B, cumulus cell-enclosed oocytes were maintained in meiotic arrest 17-18 h in … Cumulus
cell-enclosed oocytes were maintained in meiotic arrest by varying concentrations of a …

… follicle cells or the oocyte to other purine derivatives which, … , cumulus cell-enclosed and
denuded oocytes were isolated … , cumulus cell-enclosed oocytes were isolated and washed in …

… oocyte growth. This overview focusses on the role of exogenous purine nucleosides for the
growing oocytes. … male and female germ cells are not enclosed in a nutritive (follicular) tissue …

… Hypoxanthine maintained 80% of cumulus cell-enclosed oocytes in … oocyte-cumulus cell
complexes, yet this purine nucleoside increased the inhibitory effects of hypoxanthine on oocyte …

… metabolic pathways in vivo might induce the resumption of oocyte maturation. To test this …
enzymes in the purine metabolic pathways. Cumulus cell-enclosed oocytes were isolated from …

… Fully grown mammalian oocytes spontaneously resume meiotic maturation when removed
… -enclosed oocytes can be blocked in prophase I if the medium is supplemented with purines …

… To measure uptake by cumulus cell– enclosed oocytes (CEOs), … end of culture and the
oocytes were washed and processed for … Oocytes were cultured for 3 hr and purines were added …

… on oocyte maturation and de novo purine synthesis. Cumulus cell-enclosed oocytes were
… We next determined whether FSH-stimulated de novo purine synthesis is compromised in L-…

… The initial 1-h incubation assured that the drugs used had ample time to act before introduction
of the radiolabeled purine. For oocyte maturation, cumulus cell-enclosed oocytes were …