Endocannabinoid release from midbrain dopamine neurons: a potential substrate for cannabinoid receptor antagonist treatment of addiction
… the antagonism of cannabinoid CB1 … dopamine neurons, the effects of the endocannabinoids
are occluded. The data from these studies therefore suggest that the endocannabinoid …
are occluded. The data from these studies therefore suggest that the endocannabinoid …
Hub and switches: endocannabinoid signalling in midbrain dopamine neurons
… -S into DA neurons proved to block endocannabinoid-mediated … cell [33], which would release
2-AG following group I mGluR … that VTA DA neurons, by releasing endocannabinoids, can …
2-AG following group I mGluR … that VTA DA neurons, by releasing endocannabinoids, can …
Endocannabinoid signaling in midbrain dopamine neurons: more than physiology?
… In fact, endogenous cannabinoids (endocannabinoids) were discovered to play a role in the
… interaction between endocannabinoids (eCBs) and midbrain dopamine (DA) neurons, as …
… interaction between endocannabinoids (eCBs) and midbrain dopamine (DA) neurons, as …
Endocannabinoid modulation of dopamine neurotransmission
… The defining feature of a dopaminergic neuron is an ability to synthesize DA and release it
both locally and at distal axon terminals (Subramaniam and Roeper, 2017, Sulzer et al., 2017)…
both locally and at distal axon terminals (Subramaniam and Roeper, 2017, Sulzer et al., 2017)…
Protective activation of the endocannabinoid system during ischemia in dopamine neurons
… endocannabinoid signaling in the VTA, several key pieces of information are yet unknown.
Primarily, are endocannabinoids released … of cannabinoids protect DA neurons from ischemic-…
Primarily, are endocannabinoids released … of cannabinoids protect DA neurons from ischemic-…
Release of endogenous cannabinoids from ventral tegmental area dopamine neurons and the modulation of synaptic processes
… Since heightened neuronal activity facilitates eCB release in many brain regions, we sought
to determine whether bursting in VTA DA neurons augments endocannabinoid modulation …
to determine whether bursting in VTA DA neurons augments endocannabinoid modulation …
Modulating the neuromodulators: dopamine, serotonin, and the endocannabinoid system
… neurons drive reward by establishing excitatory synapses on VTA mesoaccumbens dopamine
neurons… Potential sites of cannabinoid receptor modulation of DRN 5-HT neurons. (Left) …
neurons… Potential sites of cannabinoid receptor modulation of DRN 5-HT neurons. (Left) …
Endocannabinoid signaling system and brain reward: emphasis on dopamine
EL Gardner - Pharmacology Biochemistry and Behavior, 2005 - Elsevier
… With respect to cannabinoid effects on DA release, as studied by in vitro assays, the picture
is unclear. Enhancement (Poddar and Dewey, 1980, Jentsch et al., 1998), no effect (Szabo et …
is unclear. Enhancement (Poddar and Dewey, 1980, Jentsch et al., 1998), no effect (Szabo et …
[HTML][HTML] Endocannabinoid modulation of nucleus accumbens microcircuitry and terminal dopamine release
DP Covey, AG Yocky - Frontiers in synaptic neuroscience, 2021 - frontiersin.org
… Dopamine neurons control their own activity through feedback mechanisms at axon
terminals via D2 DA autoreceptor signaling and DAT-mediated reuptake. As discussed above (…
terminals via D2 DA autoreceptor signaling and DAT-mediated reuptake. As discussed above (…
A brain on cannabinoids: the role of dopamine release in reward seeking and addiction
… This article reviews cannabinoid interactions with the dopamine … Cannabinoid-induced
increases in NAc dopamine … from an increase in the mean firing rate of dopamine neurons within …
increases in NAc dopamine … from an increase in the mean firing rate of dopamine neurons within …
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