Integrating endocannabinoid signaling and cannabinoids into the biology and treatment of posttraumatic stress disorder
… Finally, we propose that a state of endocannabinoid deficiency could represent a stress
susceptibility endophenotype predisposing to the development of trauma-related …
susceptibility endophenotype predisposing to the development of trauma-related …
Endocannabinoid signaling in psychiatric disorders: a review of positron emission tomography studies
… with anorexia nervosa and post-traumatic stress disorder, but limited data have been …
alterations in endocannabinoid signaling are present in a range of psychiatric disorders. Although …
alterations in endocannabinoid signaling are present in a range of psychiatric disorders. Although …
Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders
BB Gorzalka, MN Hill, CJ Hillard - Neuroscience & Biobehavioral Reviews, 2008 - Elsevier
… by maladaptive stress coping. In this review, we discuss the evidence demonstrating that the
endocannabinoid system is affected by and can oppose the effects of prolonged stress and, …
endocannabinoid system is affected by and can oppose the effects of prolonged stress and, …
[HTML][HTML] Targeting the endocannabinoid system in the treatment of posttraumatic stress disorder: A promising case of preclinical-clinical translation?
… Failure to extinguish traumatic memories is a core symptom of posttraumatic stress disorder,
suggesting that potentiating eCB signaling may have a therapeutic potential in this condition…
suggesting that potentiating eCB signaling may have a therapeutic potential in this condition…
Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the World Trade Center attacks
MN Hill, LM Bierer, I Makotkine, JA Golier… - …, 2013 - Elsevier
… Endocannabinoid (eCB) signaling has been identified as a modulator of adaptation to stress,
and is integral to basal and stress… development of post-traumatic stress disorder (PTSD). To …
and is integral to basal and stress… development of post-traumatic stress disorder (PTSD). To …
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure
… of affective disorders including major depression and posttraumatic stress disorder. …
stress could have broad implications for the treatment and prevention of mood and anxiety …
stress could have broad implications for the treatment and prevention of mood and anxiety …
Stress regulates endocannabinoid-CB1 receptor signaling
CJ Hillard - Seminars in immunology, 2014 - Elsevier
… Deficiency of CB1 receptor signaling is … receptor-endocannabinoid signaling is activated
by stress and functions to buffer or dampen the behavioral and endocrine effects of acute stress. …
by stress and functions to buffer or dampen the behavioral and endocrine effects of acute stress. …
Endocannabinoid signaling and epigenetics modifications in the neurobiology of stress-related disorders
AA Coelho, S Lima-Bastos, PH Gobira… - … Signaling, 2023 - portlandpress.com
… Stress exposure is associated with psychiatric conditions, such as depression, … stress
disorder (PTSD). It is also a vulnerability factor to developing or reinstating substance use disorder. …
disorder (PTSD). It is also a vulnerability factor to developing or reinstating substance use disorder. …
A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior
RJ McLaughlin, MN Hill, BB Gorzalka - Neuroscience & Biobehavioral …, 2014 - Elsevier
… flow and neuronal activity have been identified in a variety of anxiety disorders, particularly
post-traumatic stress disorder and social anxiety disorder (Freitas-Ferrari et al., 2010), and …
post-traumatic stress disorder and social anxiety disorder (Freitas-Ferrari et al., 2010), and …
… of enhancing endocannabinoid signaling and blocking corticotrophin releasing factor receptor in the amygdala and hippocampus on the consolidation of a stressful …
… Exposure to an excessive or an uncontrolled stress is a major factor associated with various
diseases including post-traumatic stress disorder (PTSD). The consequences of exposure to …
diseases including post-traumatic stress disorder (PTSD). The consequences of exposure to …
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