Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas
E Hao, B Tyrberg, P Itkin-Ansari, JRT Lakey, I Geron… - Nature medicine, 2006 - nature.com
… We next asked whether fetal pancreatic factors might enhance the partial endocrine
differentiation of adult cells seen after subcapsular renal transplantation. Lentiviral vectors, which …
differentiation of adult cells seen after subcapsular renal transplantation. Lentiviral vectors, which …
[PDF][PDF] Beta cell differentiation during early human pancreas development
K Piper, S Brickwood, LW Turnpenny… - … of Endocrinology, 2004 - Citeseer
… To address these questions, in this immunohistochemical study we describe beta cell
differentiation in precisely staged human embryonic and early fetal material, correlated to cell …
differentiation in precisely staged human embryonic and early fetal material, correlated to cell …
Chronology of endocrine differentiation and beta-cell neogenesis
T Miyatsuka - Endocrine Journal, 2016 - jstage.jst.go.jp
… to reveal the unique features of each endocrine cell type at distinct developmental time
points. … and endocrine differentiation focusing on recent progresses in improving temporal cell …
points. … and endocrine differentiation focusing on recent progresses in improving temporal cell …
Single-cell gene expression analysis of a human ESC model of pancreatic endocrine development reveals different paths to β-cell differentiation
MBK Petersen, A Azad, C Ingvorsen, K Hess… - Stem cell reports, 2017 - cell.com
… across several stages of in vitro differentiation of hESCs and compared … the endocrine
differentiation path and an early lineage bifurcation toward either polyhormonal cells or β-like cells…
differentiation path and an early lineage bifurcation toward either polyhormonal cells or β-like cells…
The endocrine pancreas: insights into development, differentiation, and diabetes
TL Mastracci, L Sussel - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
… cells that form the endocrine progenitor population, and by late gestation is selectively maintained
at high levels in the β cells and lower levels in the acinar cells… endocrine differentiation.…
at high levels in the β cells and lower levels in the acinar cells… endocrine differentiation.…
Retinoic acid promotes the generation of pancreatic endocrine progenitor cells and their further differentiation into β-cells
M Öström, KA Loffler, S Edfalk, L Selander, U Dahl… - PloS one, 2008 - journals.plos.org
… of pancreatic endocrine cell differentiation, we provide evidence that RA promotes both
the generation of Ngn3 + endocrine progenitor cells and their further differentiation into β-cells. …
the generation of Ngn3 + endocrine progenitor cells and their further differentiation into β-cells. …
Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells
… A time-course analysis of endocrine differentiation from pancreatic progenitors (d11) to …
of C-peptide + cells and increasing co-expression of endocrine/β-cell-specific markers of …
of C-peptide + cells and increasing co-expression of endocrine/β-cell-specific markers of …
Glucose is necessary for embryonic pancreatic endocrine cell differentiation
G Guillemain, G Filhoulaud, G Da Silva-Xavier… - Journal of Biological …, 2007 - ASBMB
… Such an effect of glucose on beta cell differentiation could be mimicked neither by l-glucose
nor by xylose. We next asked whether the lack of endocrine cell differentiation in the …
nor by xylose. We next asked whether the lack of endocrine cell differentiation in the …
Charting cellular identity during human in vitro β-cell differentiation
A Veres, AL Faust, HL Bushnell, EN Engquist… - Nature, 2019 - nature.com
… pancreatic endocrine cells, from which we develop a lineage model of in vitro β-cell
differentiation… Beta cells are front-runners in the field of regenerative medicine. Nonetheless, …
differentiation… Beta cells are front-runners in the field of regenerative medicine. Nonetheless, …
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture
R Gao, J Ustinov, MA Pulkkinen, K Lundin… - Diabetes, 2003 - Am Diabetes Assoc
… endocrine cells present in the CHIBs have differentiated in vitro and do not result from the
migration of preexisting islet cells… Bouwens L, Pipeleers DG: Extra-insular beta cells associated …
migration of preexisting islet cells… Bouwens L, Pipeleers DG: Extra-insular beta cells associated …
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