… signalling events in vivo during B-cell maturation were visualized. Here we show that B cells
encounter antigen during development in the spleen, and that this antigen exposure, in turn, …

… endogenous antigen-specific cells limits current understanding of this process. Using an …
is initiated when naïve B cells expressing surface immunoglobulin (Ig) bind the antigen in …

… ) Histograms represent intracellular Nur77 and surface CD69 expression in total human
CD20+ B cells, naive (CD20+IgM+CD27−) B cells, and memory (CD20+IgM+CD27+) …

… naive B cells in the immunogenicity of HBcAg is not clear. The HBcAg-binding properties of
naive B cells … To study the role of B cells in priming CTLs by endogenously and exogenously …

… B cell function. These include the low frequency of naïve B cells that bear a receptor for a
particular antigen… to evaluate antigen presentation of a transgene-encoded endogenous protein…

… studying B cell responses to phycoerythrin (PE). PE immunization of mouse strains with Igh b
… genes elicited affinity-matured switched Ig memory B cells that declined with time, while the …

… antigen from antigen-specific B cells to endogenous antigen-… process of antigen transfer by
B cells to an endogenous APC … of antigen by tolerant B cells, naive B cells, or after transfer of …

… of reported frequencies (10 –5 –10 –4 ) of endogenous B cells specific to a particular antigen
27,28 and could be supported by the endogenous OVA-specific Th repertoire (Fig. 2i–l). …

… These results appear to conflict with the results of a recent study that found low Nur77 eGFP
levels in NP-specific B cells using a transgenic H chain paired to endogenously produced λ (…

… Naive, long-lived B cells in rodents and humans are heterogeneous … endogenous
immunoglobulin genes. The net result of the driving forces of environmental and endogenous …