… stress. In this review I summarize how perturbation of three major functions of the endoplasmic
reticulum … stress and activates signaling pathways collectively termed the unfolded protein …

… Che P, Howell SH, 2007; An endoplasmic reticulum stress response in Arabidopsis is mediated
by proteolytic processing and nuclear relocation of a membrane-associated transcription …

… To restore ER functioning, specific stress responses are activated one of which is the unfolded
protein response (UPR). UPR is characterized by a shutdown of global protein synthesis …

Inability to meet protein folding demands within the endoplasmic reticulum (ER) activates
the unfolded protein response (UPR), a signaling pathway with both adaptive and apoptotic …

… The second component of the ER stress response, which represents the focus of this article,
… The third, less well-characterized aspect of the ER stress response causes programmed cell …

… sources of cellular stress have also … stress arises in the endoplasmic reticulum (ER) of cells
following the accumulation of misfolded proteins during protein synthesis (known as ER stress…

… When cells are exposed to a severe form of stress, stress responses are activated that are
highly conserved from yeast to mammalian cells. These stress responses comprise activation …

In eukaryotic cells, the endoplasmic reticulum (ER) is an organelle that is responsible for
protein folding and assembly, lipid and sterol biosynthesis, and free calcium storage. In the past …

… response? Does the signalling in stress responses and inflammatory responses stem from
a common mechanism or from different mechanisms that subsequently become integrated? …

… unfolded protein response (UPR). We review the evidence suggesting that the ER stress
response could be important for the growth and development of tumors under stressful growth …