Endoplasmic reticulum stress signalling–from basic mechanisms to clinical applications

A Almanza, A Carlesso, C Chintha… - The FEBS …, 2019 - Wiley Online Library
… Specific ER stress signalling pathways, collectively known as … In this review, we provide a
UPR signalling‐centric view of … Our review provides a synthesis of intracellular ER signalling

Endoplasmic reticulum: stress, signalling and apoptosis

SG Hussain, KVA Ramaiah - Current science, 2007 - JSTOR
… and Lee, AS, Endoplasmic reticulum stress induced apoptosis: Multiple … endoplasmic
reticulum (ER) mediates ER stress signalling for activation of caspase-12 during ER stress

[HTML][HTML] The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

NJ Darling, SJ Cook - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
… or death responses following a variety of stresses. In this article, we review UPR signalling
and the activation of MAPK signalling pathways in response to ER stress. In addition, we …

Endoplasmic reticulum stress signaling in disease

SJ Marciniak, D Ron - Physiological reviews, 2006 - journals.physiology.org
… by a membranous network called the endoplasmic reticulum (ER). With evolution of …
endoplasmic reticulum “client” proteins presents unique dangers to the cell and is termed “ER stress

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease

C Lebeaupin, D Vallée, Y Hazari, C Hetz, E Chevet… - Journal of …, 2018 - Elsevier
… Dysfunction of the endoplasmic reticulum (ER), the main cellular … of ER stress signalling.
This review compiles the recent findings supporting the functional impact of ER stress signalling

Messenger RNA targeting to endoplasmic reticulum stress signalling sites

T Aragón, E Van Anken, D Pincus, IM Serafimova… - Nature, 2009 - nature.com
… Deficiencies in the protein-folding capacity of the endoplasmic reticulum (ER) in all
eukaryotic cells lead to ER stress and trigger the unfolded protein response (UPR) 1 , 2 , 3 . ER …

Endoplasmic reticulum stress signals in the tumour and its microenvironment

X Chen, JR Cubillos-Ruiz - Nature Reviews Cancer, 2021 - nature.com
… of ER stress in the tumour milieu, the interplay between oncogenic signalling and ER stress
… and the profound immunomodulatory effects of sustained ER stress responses in tumours. …

Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis

Y Dong, C Fernandes, Y Liu, Y Wu… - Diabetes and …, 2017 - journals.sagepub.com
… persistent, endoplasmic reticulum stress response could … in understanding endoplasmic
reticulum stress-induced … atherosclerosis and endoplasmic reticulum stress as a potential …

Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1

B Li, P Yi, B Zhang, C Xu, Q Liu, Z Pi, X Xu, E Chevet… - Cellular signalling, 2011 - Elsevier
Endoplasmic reticulum (ER) stress signalling pathways are involved in various alterations
of the central nervous system such as neurodegenerative diseases or ischemia. The current …

From endoplasmic-reticulum stress to the inflammatory response

K Zhang, RJ Kaufman - Nature, 2008 - nature.com
… In mammals, IRE1α might be important for integrating ER-stress signalling with
inflammatory-response signalling. This is thought to occur in the following manner. In response to ER …