Mechanism of endothelial dysfunction in apolipoprotein E–deficient mice

LV d'Uscio, TA Baker, CB Mantilla, L Smith… - … , and vascular biology, 2001 - Am Heart Assoc
… in a mouse model of human atherosclerosis. Our objective was to characterize the mechanisms
underlying endothelial dysfunction in aortas of apolipoprotein E (apoE)-deficient mice, …

[HTML][HTML] ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet

N Terasaka, S Yu, L Yvan-Charvet… - The Journal of …, 2008 - Am Soc Clin Investig
endothelial dysfunction (20–22). Our studies revealed a non-redundant role of ABCG1 and
a lesser role of ABCA1 in preserving endothelial eNOS activity in mice … to defend endothelial

SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein

C Iadecola, F Zhang, K Niwa, C Eckman… - Nature …, 1999 - nature.com
… lack of endothelial dysfunction in APP + /SOD1 + mice could be … of wild–type human APP
transgenic mice (Tg6209) that expresses … 3 ), Tg6209 mice showed alterations in endothelium–…

Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell

T Bai, M Li, Y Liu, Z Qiao, Z Wang - Free Radical Biology and Medicine, 2020 - Elsevier
… In order to confirm our hypothesis, ApoE −/- mice were fed with high fat diet (HFD) to induce
… peroxidation and endothelial dysfunction in ox-LDL-treated mouse aortic endothelial cells (…

Mitochondria‐targeted antioxidant (MitoQ) ameliorates age‐related arterial endothelial dysfunction in mice

RA Gioscia‐Ryan, TJ LaRocca… - The Journal of …, 2014 - Wiley Online Library
… , MitoQ, ameliorates vascular endothelial dysfunction in old mice and that these improvements
are … vascular endothelial dysfunction and therefore may be a promising therapeutic target. …

Trimethylamine-N-oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans

VE Brunt, RA Gioscia-Ryan, AG Casso… - …, 2020 - Am Heart Assoc
endothelial dysfunction to levels observed in young mice via normalization of oxidative stress
and NO bioavailability. Lastly, we show that the greater endothelial dysfunctionendothelial

Inhibition of MPO (myeloperoxidase) attenuates endothelial dysfunction in mouse models of vascular inflammation and atherosclerosis

D Cheng, J Talib, CP Stanley, I Rashid… - … , and vascular biology, 2019 - Am Heart Assoc
… systemic endothelial dysfunction, we assessed endothelial function in the abdominal aorta of
the femoral artery-cuffed mice… Apoe −/− mice (Figure 1B, left) without obvious effects on the …

[HTML][HTML] Periodontitis induces endothelial dysfunction in mice

M Parvaneh, PK Witting, J Ku, T Moradi, E Eroglu… - Scientific Reports, 2021 - nature.com
… the early stages of endothelial dysfunction that is linked to … Endothelial dysfunction is an
early pathogenic event of … significantly associated with endothelial dysfunction as measured by …

Endothelial nitric oxide synthase transgenic models of endothelial dysfunction

DN Atochin, PL Huang - Pflügers Archiv-European Journal of Physiology, 2010 - Springer
… on mouse models of endothelial dysfunctionendothelial dysfunction in mouse models of
atherosclerosis and diabetes. This review focuses on mouse models of endothelial dysfunction

[HTML][HTML] Endothelial dysfunction in the apolipoprotein E-deficient mouse: insights into the influence of diet, gender and aging

SS Meyrelles, VA Peotta, TMC Pereira… - Lipids in health and …, 2011 - Springer
… into the mouse allowing the development of mouse models for … E-deficient (apoE -/- ) mouse,
which is considered the best … underlying endothelial dysfunction in the apoE -/- mouse and …