Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
… Biomaterials can promote specific targeting of immune cell … Here, we review recent advances
in biomaterials-based … , tissue-resident immune cells and immune cells at disease sites. …
in biomaterials-based … , tissue-resident immune cells and immune cells at disease sites. …
Engineering biomaterials to direct innate immunity
… with adaptive immune cells have informed immune engineered materials that target specific
… that genetically engineering innate immune mechanisms to control cell function can combat …
… that genetically engineering innate immune mechanisms to control cell function can combat …
Engineered biomaterials for in situ tissue regeneration
… Depending on the biophysical and biochemical characteristics of the biomaterial, immune
cells … from immune cells helps in the recruitment of endogenous progenitor stem cells. These …
cells … from immune cells helps in the recruitment of endogenous progenitor stem cells. These …
Biomaterial-assisted targeted modulation of immune cells in cancer treatment
… These tumour cells can also be engineered to express pro-inflammatory cytokines such as
… exist to achieve broad clinical efficacy with immune cell targeting biomaterials, including non-…
… exist to achieve broad clinical efficacy with immune cell targeting biomaterials, including non-…
Engineered biomaterials for cancer immunotherapy
… immune cells are recruited to the implant site. Examples of … engineered biomaterials to act
as reservoirs or drug carriers. As described in this review (Table 1), engineered biomaterials …
as reservoirs or drug carriers. As described in this review (Table 1), engineered biomaterials …
Engineering Biomaterials to Model Immune‐Tumor Interactions In Vitro
… In this section, we discuss common strategies, summarized in Figure 3, to create
biomaterial-based scaffolds in which immune cells to reside and their subsequent impact on …
biomaterial-based scaffolds in which immune cells to reside and their subsequent impact on …
Engineering immune tolerance with biomaterials
… of immune signals and promote migration of immune cells. This allows the engineering of a
… intrinsic immunogenic properties of biomaterials modulate immune cell function, and how …
… intrinsic immunogenic properties of biomaterials modulate immune cell function, and how …
Extracellular matrix‐based strategies for immunomodulatory biomaterials engineering
AT Rowley, RR Nagalla, SW Wang… - Advanced healthcare …, 2019 - Wiley Online Library
… These domains can be functionalized into biomaterials to regulate specific immune cell
functions. This section will focus on engineering ECM-derived peptides into various materials for …
functions. This section will focus on engineering ECM-derived peptides into various materials for …
Designing biomaterials with immunomodulatory properties for tissue engineering and regenerative medicine
JI Andorko, CM Jewell - Bioengineering & translational …, 2017 - Wiley Online Library
… applications, the studies in this section highlight opportunities to modulate immune cell
phenotypes by altering the hydrophobicity, charge, or surface chemical functional groups of …
phenotypes by altering the hydrophobicity, charge, or surface chemical functional groups of …
Biomimetic tissue engineering: tuning the immune and inflammatory response to implantable biomaterials
F Taraballi, M Sushnitha, C Tsao… - Advanced …, 2018 - Wiley Online Library
… functionalization is aimed at directly mediating the interactions of the biomaterial with
immune cells, resulting in reduced scar formation or induction of macrophage polarization. …
immune cells, resulting in reduced scar formation or induction of macrophage polarization. …
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