Biological characteristics of exosomes and genetically engineered exosomes for the targeted delivery of therapeutic agents
Y Lin, Y Lu, X Li - Journal of Drug Targeting, 2020 - Taylor & Francis
… To improve the delivery of therapeutic messages to cardiac cells, exosomes must be
engineered to modify their cargo and membranes [Citation146]. Therapeutic exosomes could be …
engineered to modify their cargo and membranes [Citation146]. Therapeutic exosomes could be …
Targeted therapeutic delivery using engineered exosomes and its applications in cardiovascular diseases
D Xitong, Z Xiaorong - Gene, 2016 - Elsevier
… The molecules encapsulated into ILVs are not a random but a selective regulated process,
leading to the profile of cargo molecules inside the exosomes, albeit reflecting the nature and …
leading to the profile of cargo molecules inside the exosomes, albeit reflecting the nature and …
[HTML][HTML] Exosome engineering: Current progress in cargo loading and targeted delivery
S Fu, Y Wang, X Xia, JC Zheng - NanoImpact, 2020 - Elsevier
… and functions) of exosome, summarize currently available methodologies for exosomal cargo
loading, review the progress in exosome engineering techniques for targeted delivery, and …
loading, review the progress in exosome engineering techniques for targeted delivery, and …
[HTML][HTML] Engineering exosomes for targeted drug delivery
… engineering of exosomes for targeted drug delivery. In this review, we will introduce the
characteristics of exosomes … Membrane-bound antigen cargo can also be displayed by the C1C2 …
characteristics of exosomes … Membrane-bound antigen cargo can also be displayed by the C1C2 …
Engineering Approaches for Exosome Cargo Loading and Targeted Delivery: Biological versus Chemical Perspectives
… In addition, we provide an overview of the advances in the use of engineered exosomes for
… of chemically engineered versus bioengineered exosome-mediated target therapies. These …
… of chemically engineered versus bioengineered exosome-mediated target therapies. These …
Biodistribution of exosomes and engineering strategies for targeted delivery of therapeutic exosomes
H Choi, Y Choi, HY Yim, A Mirzaaghasi, JK Yoo… - Tissue engineering and …, 2021 - Springer
… of exosomes. Recent advances accentuate the potential of targeted delivery of engineered
exosomes … and PK of exosomes, as well as exosomal surface engineering technologies for …
exosomes … and PK of exosomes, as well as exosomal surface engineering technologies for …
Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers
N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
… ® platform for engineering exosome-based therapeutics production for … of engineering
exosomes, they focus on both cargo … Their focus is mainly on therapeutic RNA as the cargo. The …
exosomes, they focus on both cargo … Their focus is mainly on therapeutic RNA as the cargo. The …
Engineered exosomes from different sources for cancer-targeted therapy
M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - … and targeted therapy, 2023 - nature.com
… decorated with specific targeted molecules, including peptides, can achieve more precise
therapeutic cargo delivery. The miR-HER2 (human epidermal growth factor receptor 2)-loaded …
therapeutic cargo delivery. The miR-HER2 (human epidermal growth factor receptor 2)-loaded …
Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
… engineering exosomes and evaluating their drug delivery effects, and current techniques for
assessing exosome … , pharmacokinetics, and therapeutic outcomes are critically examined. …
assessing exosome … , pharmacokinetics, and therapeutic outcomes are critically examined. …
FedExosomes: engineering therapeutic biological nanoparticles that truly deliver
ME Marcus, JN Leonard - Pharmaceuticals, 2013 - mdpi.com
… exosomes for therapeutic RNA delivery, discuss the potential for engineering exosomes
to … process, which we discuss below when considering specific types of exosomal cargo. …
to … process, which we discuss below when considering specific types of exosomal cargo. …
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