Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain
… Lastly, BBB transport pathways can be altered to increase nanomaterial transport. In this review,
… have been exploited by engineered nanomaterials for increased transport into the brain. …
… have been exploited by engineered nanomaterials for increased transport into the brain. …
The neurotoxicity induced by engineered nanomaterials
D Ge, Q Du, B Ran, X Liu, X Wang, X Ma… - International journal …, 2019 - Taylor & Francis
… Figure 1 Possible ways in which engineered nanomaterials (ENMs) cross the blood–brain
barrier (BBB) and the potential risks. ENMs with specific physicochemical properties could …
barrier (BBB) and the potential risks. ENMs with specific physicochemical properties could …
Physicochemical properties of engineered nanomaterials that influence their nervous system distribution and effects
RA Yokel - Nanomedicine: Nanotechnology, Biology and Medicine, 2016 - Elsevier
… This critical review examines in vitro and in vivo evidence for the influence of engineered
nanomaterial (ENM) physicochemical properties on their distribution into, and effects on, the …
nanomaterial (ENM) physicochemical properties on their distribution into, and effects on, the …
Nanomaterial-based blood-brain-barrier (BBB) crossing strategies
Increasing attention has been paid to the diseases of central nervous system (CNS). The
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to the …
penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to the …
The neurotoxic potential of engineered nanomaterials
… The expanding development and production of engineered nanomaterials (ENMs) have
diverse and far-reaching potential benefits in consumer products, food, drugs, medical devices …
diverse and far-reaching potential benefits in consumer products, food, drugs, medical devices …
Engineered nanoparticles. How brain friendly is this new guest?
FA Cupaioli, FA Zucca, D Boraschi, L Zecca - Progress in neurobiology, 2014 - Elsevier
… Therefore, understanding the environmental and health impact of engineered nanomaterials
and by-products has become a priority both for ensuring health protection and for …
and by-products has become a priority both for ensuring health protection and for …
Drug delivery to the brain across the blood–brain barrier using nanomaterials
… In this study, the team developed PEG-cRGD micelles to enhance the penetration of the
blood brain tumor barrier (BBTB). The results indicated that the cRGD-installed micelles possess …
blood brain tumor barrier (BBTB). The results indicated that the cRGD-installed micelles possess …
Functionalized nanomaterials capable of crossing the blood–brain barrier
… The mechanisms for BBB crossing of various nanomaterials and their cargos are also
explained. Moreover, we highlight the advantages of implementing nanomaterials as carriers for …
explained. Moreover, we highlight the advantages of implementing nanomaterials as carriers for …
Overcoming the blood–brain barrier: the role of nanomaterials in treating neurological diseases
… This is largely due to the blood–brain barrier (BBB), arguably … Advances in the engineering
of nanomaterials and their … can be delivered to the brain are examined and key challenges …
of nanomaterials and their … can be delivered to the brain are examined and key challenges …
Biodistribution and biopersistence of ceria engineered nanomaterials: size dependence
… Based on the rat brain vascular volume (2% of … in blood determined in this study, the cerium
in the brain of ceria-ENM treated rats can be accounted for by the cerium in circulating blood …
in the brain of ceria-ENM treated rats can be accounted for by the cerium in circulating blood …
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