[HTML][HTML] Age-related macular degeneration: genetic and environmental factors of disease

Y Chen, M Bedell, K Zhang - Molecular interventions, 2010 - ncbi.nlm.nih.gov
… Age-related macular degeneration (AMD) is the most common … of multiple genetic and
environmental factors. The identification … to environmental factors could reveal gene-environment

Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors

Y Chen, J Zeng, C Zhao, K Wang, E Trood… - Archives of …, 2011 - jamanetwork.com
… Our results showed that of the environmental risk factors, smoking and age were identified
as major risk factors, which was consistent with the combined analysis of population-based …

[HTML][HTML] Genetic and environmental factors strongly influence risk, severity and progression of age-related macular degeneration

W Wang, K Gawlik, J Lopez, C Wen, J Zhu… - Signal transduction and …, 2016 - nature.com
… Age-related macular degeneration (AMD) is characterized by complex interactions
between genetic and environmental factors. Here we genotyped the selected 25 single-nucleotide …

Five-year incidence, progression, and risk factors for age-related macular degeneration: the age, gene/environment susceptibility study

F Jonasson, DE Fisher, G Eiriksdottir, S Sigurdsson… - Ophthalmology, 2014 - Elsevier
… The AGES trial, as described in detail elsewhere, is a population-based study aimed to
investigate genetic and environmental factors contributing to health, disability, and disease in …

Nature and nurture-genes and environment-predict onset and progression of macular degeneration

L Sobrin, JM Seddon - Progress in retinal and eye research, 2014 - Elsevier
… Age-related macular degeneration (… environmental and genetic factors contribute to the
development of this disease. Among environmental factors, smoking, obesity and dietary factors

[HTML][HTML] Genetic and environmental risk factors for age-related macular degeneration in persons 90 years and older

L Ersoy, T Ristau, M Hahn, M Karlstetter… - … & visual science, 2014 - iovs.arvojournals.org
… For the logistic regression analyses of environmental factors, we included smoking (ever/never
smoker), hypertension, diabetes, BMI (normal/overweight/obese), and sex. Odds ratios (…

The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences

JM Seddon, J Cote, WF Page, SH Aggen… - Archives of …, 2005 - jamanetwork.com
Environmental factors unique to each … ) environmental factors should correlate perfectly in
both MZ and DZ twin pairs. In practice, measurement error and unique environmental factors

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors

JM Seddon, R Reynolds, Y Yu, MJ Daly, B Rosner - Ophthalmology, 2011 - Elsevier
… Covariates included demographic and environmental factors, 6 variants in 5 genes, baseline
macular drusen size, and presence and type of advanced AMD in 1 eye at baseline. To …

Genetic factors of age-related macular degeneration

J Tuo, CM Bojanowski, CC Chan - Progress in retinal and eye research, 2004 - Elsevier
… Age-related macular degeneration (AMD) is a leading cause of blindness in the United … , a
complex interaction of genetic and environmental factors is thought to exist. The incidence and …

Risk factors for progression of age‐related macular degeneration

TJ Heesterbeek, L Lorés‐Motta… - Ophthalmic and …, 2020 - Wiley Online Library
… , environmental, genetic, and molecular risk factors for disease progression in age-related
macular degeneration… In addition, we describe the most promising risk factors that could …