Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

M Moroni, S Veronese, S Benvenuti… - The lancet …, 2005 - thelancet.com
Background The antiepidermal growth factor receptor (antiEGFR) monoclonal antibodies
cetuximab and panitumumab have good clinical activity in about 10% of patients with …

[HTML][HTML] … among patients with human epidermal growth factor-2-positive breast cancer in the National Comprehensive Cancer Network: a prospective cohort study

I Vaz-Luis, RA Ottesen, ME Hughes, PK Marcom… - … Cancer Research, 2012 - Springer
Introduction In gene expression experiments, hormone receptor (HR)-positive/human
epidermal growth factor-2 (HER2)-positive tumors generally cluster within the luminal B subset; …

Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
… (TKIs) in patients with advanced epidermal growth factor receptor (EGFR)-mutated non–small-…
Therefore, the aim of this study was to assess the overall survival (OS) of advanced EGFR-…

Human epidermal growth factor 2 (HER2) in early stage uterine serous carcinoma: a multi-institutional cohort study

BK Erickson, O Najjar, S Damast, A Blakaj… - Gynecologic …, 2020 - Elsevier
… One such molecular target is human epidermal growth factor receptor 2 (HER2), also known
… Therefore, our study objective was to determine whether HER2 is a prognostic biomarker in …

[HTML][HTML] Urinary epidermal growth factor/creatinine ratio and graft failure in renal transplant recipients: a prospective cohort study

M Yepes-Calderón, CG Sotomayor, M Kretzler… - Journal of clinical …, 2019 - mdpi.com
… Urinary epidermal growth factor (uEGF) is involved in kidney tissue integrity, with a … In this
prospective cohort study, RTR with a functioning allograft ≥1-year were recruited and followed-…

[HTML][HTML] … pathological complete response as a biomarker of survival in human epidermal growth factor receptor-2 enriched breast cancer–a retrospective cohort study

MG Davey, E Kerin, C O'Flaherty, E Maher, V Richard… - The Breast, 2021 - Elsevier
Background Human epidermal growth factor receptor-2 (HER2) is overexpressed in 20–25%
of breast cancers. Complete eradication of disease following neoadjuvant therapies and …

[HTML][HTML] The SystHERs registry: an observational cohort study of treatment patterns and outcomes in patients with human epidermal growth factor receptor 2–positive …

D Tripathy, HS Rugo, PA Kaufman, S Swain… - BMC cancer, 2014 - Springer
… Amplification of the human epidermal growth factor receptor 2 (HER2) gene occurs in …
A prospective, observational cohort study was designed and initiated to provide real-world …

… advanced human epidermal growth Factor–2-Positive breast cancer with prolonged clinical benefit to first-line trastuzumab-based therapy: a retrospective cohort study

I Vaz-Luis, D Seah, EM Olson, N Wagle… - Clinical breast …, 2013 - Elsevier
Background The magnitude of benefit of trastuzumab for the treatment of advanced HER2-positive
breast cancer varies widely. In this retrospective study, we investigated the …

The role of radiotherapy in epidermal growth factor receptor mutation-positive patients with oligoprogression: a matched-cohort analysis

OSH Chan, VHF Lee, TSK Mok, F Mo, ATY Chang… - Clinical Oncology, 2017 - Elsevier
… in a randomised study. Considering the potential ethical implication, a randomised comparative
study can be challenging. Here we report a matched-cohort study comparing patients …

… human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer: a cohort study

N Sneige, KR Hess, AS Multani, Y Gong, NK Ibrahim - Cancer, 2017 - Wiley Online Library
… Human epidermal growth factor receptor 2 (HER2), a member of the epidermal growth
factor receptor family, is encoded by a gene (HER2 or ERBB2) located on the long arm of …