… The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein that … kinase
receptors. Binding of EGFR to its cognate ligands leads to autophosphorylation of receptor …

… of the epidermal growth factor (EGF) receptor (EGFR), … epidermal growth factor receptor
(EGFR) regulates the intracellular effects of ligands such as EGF and transforming growth factor-…

… The epidermal growth factor (EGF) receptor (R) belongs to the ErbB family of receptor
tyrosine kinases (RTKs). These receptors possess protein tyrosine kinase (PTK) activity and are …

… transforming growth factor-α (TGF-α) bound to the EGFR can already dissociate from the
receptor … to EGFR recycling as compared to the lysosomal degradation of EGF-bound receptors. …

… for proteins that are either growth factors, or growth factor receptors, or proteins that are
involved in the intracellular signal transduction pathway for growth factors. In addition, activated …

… of the epidermal growth factor receptor are among the most notable cancer molecular
targets identified to date epidermal growth factor receptorepidermal growth factor receptor (EGFR)/…

… The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that plays a … this
receptor has yet to be determined, but intense investigations of fragments of the receptor have …

… ligands for EGFR include epidermal growth factor (EGF), transforming growth factor-α (TGF-…
Ligand binding to ErbB receptors induces the formation of receptor homo- and heterodimers …

… The development and clinical application of inhibitors that target the epidermal growth factor
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …

… The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase receptor that is …
in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor. …