The development and clinical application of inhibitors that target the epidermal growth factor
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …

… EGFR belongs to the HER/ErbB family of growth factor receptors. These receptors consist of
… Activating mutations in the epidermal growth factor receptor underlying responsiveness of …

… therapeutics, the discovery of mutations in epidermal growth factor receptor (EGFR) in 15–20…
responses despite presence of activating EGFR mutations. epidermal growth factor receptor …

… Activating mutations in the epidermal growth factor receptor gene (EGFR) confer …
EGFR mutations in such patients and analyzed the association between the mutations and …

… Several types of epidermal growth factor receptor (EGFR)gene mutations have been …
diversity of EGFR mutations in glioblastomas and to determine whether gene mutation is inevitably …

… Research in the past year has shown that these mutations in NSCLC … mutant epidermal
growth factor gene into host cell lines confers sensitivity to gefitinib and erlotinib, and mutations …

… that epidermal growth factor receptor (EGFR) mutations are prevalent in female nonsmokers.
However, EGFR mutations … to address mutation incidence. Because the incidence of EGFR …

Novel therapeutic agents targeting the epidermal growth factor receptor (EGFR) have improved
outcomes for a subgroup of patients with colorectal, lung, head and neck, and pancreatic …

… Locations and types of the 134 epidermal growth factor receptor (EGFR) gene mutations …
types of the mutations in the tyrosine kinase (TK) domain are shown at right. All mutations were …

The epidermal growth factor receptor (EGFR) has emerged as an attractive therapeutic
target for patients with non–small-cell lung cancer (NSCLC). However, despite its almost …