… However, there are still numerous barriers to overcome. … DNA methylation machinery
and reduces unwanted … of any epigenetic editor for targeted DNA methylation must be a …

… overcome the genetic barriers associated with introductions (eg, … DNA methylation among
cities throughout the range expansion of house sparrows in Kenya. We described epigenetic …

… modifications, the preponderance of studies to date have focused on DNA methylation.
From this work, altered DNA methylation in immune cells has been shown in multiple immune-…

… Increasing evidence suggests that epigenetic regulation is … substrate for epigenetic marking,
including DNA methylation, post-… appears to be a crucial barrier that must be surmounted for …

… Given the critical role of uhrf1 in maintaining DNA methylation, we hypothesized that the …
of DNA methylation and epigenetic repression at the tnfa promoter leads to intestinal barrier …

… In mammary epithelial cells that had overcome a stress-associated senescence barrier, a
spreading of DNA methylation in the CpG island promoter was observed. When the RASSF1A-…

… The epigenetic potential of DNA methylation inhibitors may be limited by other epigenetic …
abnormalities in cancer suggest, several barriers need to be overcome: drug delivery, …

… Then, we highlight the relevance of DNA methylation variation as an evolutionary … knowledge
of the population epigenetics field. As for our results, DNA methylation diversity was found …

… In this study, we aimed to explore endogenous signatures and detect potential reprogramming
barriers based on published DNA methylation [17]. First, we summarized the global …

… are directed by epigenetic mechanisms such as DNA methylation or … epigenetic mechanisms
like microRNAs, long non-coding RNAs, and histone variants [1, 2]. These epigenetic …