[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications

Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
… -modifying enzymes may represent an efficient for treating cancer. In this review, we outlined
the biological function of ZEB1 in tumorigenic progression and epigenetic modifications

Epigenetic regulation in cancer progression

E Baxter, K Windloch, F Gannon, JS Lee - Cell & bioscience, 2014 - Springer
… of epigenetic changes that can occur and will discuss how deregulation of epigenetic modifiers
contributes to cancer progression. … may play an important role in tumorigenesis. However, …

Cancer development, progression, and therapy: an epigenetic overview

S Sarkar, G Horn, K Moulton, A Oza, S Byler… - International journal of …, 2013 - mdpi.com
… genes to inhibit tumorigenesis. … cancer progression in which epigenetic changes play a key
role in the development of these clinically significant cell features [5]. Epigenetic changes can …

Epigenetic gene silencing in cancer initiation and progression

KP Nephew, THM Huang - Cancer letters, 2003 - Elsevier
… to reconstruct epigenetic progression during tumorigenesis. … changes in DNA sequence.
Methylation of cytosine residues at CpG dinucleotides is the major epigenetic modification

[HTML][HTML] Epigenetic alterations in cancer

S Ilango, B Paital, P Jayachandran… - Frontiers in Bioscience …, 2020 - imrpress.com
… tumor progression and their relevance to epigenetic therapy. … phenomena like nucleosome
remodelling by histone modifications, … towards tumorigenesis are regulated. The alliance of …

Epigenetic modifications as therapeutic targets

TK Kelly, DD De Carvalho, PA Jones - Nature biotechnology, 2010 - nature.com
… in which epigenetic modifications have been used to evaluate disease risk, progression and
… silencing mechanisms may provide new avenues to evaluate the tumorigenic potential of …

… epigenetic mechanisms of tumor progression: Induction of high‐frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties …

RS Kerbel, P Frost, R Liteplo… - Journal of Cellular …, 1984 - Wiley Online Library
… By “epigenetic” we mean a heritable phenotypic change in a cell population brought about
… of epigenetic mechanisms being involved in some aspects of tumor progression and quite …

Epigenetic regulation and cancer

QW Chen, XY Zhu, YY Li, ZQ Meng - Oncology reports, 2014 - spandidos-publications.com
… to participate in the pro-tumorigenic network resulting from MYC … -146 to prostate cancer
progression has been identified in its … that epigenetic changes are main factors in tumorigenesis

Epigenetic modifications of c-MYC: Role in cancer cell reprogramming, progression and chemoresistance

H Fatma, SK Maurya, HR Siddique - Seminars in cancer biology, 2022 - Elsevier
… Recent studies reported that ncRNA are linked to tumorigenesis via genetic and epigenetic
alterations [67]. For example, HDAC1 positively regulates c-MYC, which further targets …

Metabolic dysregulations and epigenetics: a bidirectional interplay that drives tumor progression

F Crispo, V Condelli, S Lepore, T Notarangelo… - Cells, 2019 - mdpi.com
… Aberrant epigenetic patterns are crucial in tumorigenesis, especially DNA and … influence
epigenetic mechanisms and sustain tumor progression, equally epigenetic modifications might …