Perturbation of cellular mechanistic system by silver nanoparticle toxicity: Cytotoxic, genotoxic and epigenetic potentials
… Various molecular factors get provoked in response to Ag NPs which leads to stimulation
of several signaling pathways which eventually decides the cellular fate or level of toxicity. …
of several signaling pathways which eventually decides the cellular fate or level of toxicity. …
A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat
M Marin-Kuan, S Nestler, C Verguet… - Toxicological …, 2006 - academic.oup.com
… mechanistic understanding of OTA toxicity, particularly in … -signaling pathways known to be
involved in carcinogenesis. They include modulation of the calcium-dependent signaling and …
involved in carcinogenesis. They include modulation of the calcium-dependent signaling and …
Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells
P Babica, R Zurabian, ER Kumar, R Chopra… - Toxicological …, 2016 - academic.oup.com
… genomic signaling. Such alterations of rapid intercellular and intracellular signaling events
… , could also contribute to transgenerational epigenetic effects of endocrine disruptors. …
… , could also contribute to transgenerational epigenetic effects of endocrine disruptors. …
Epigenetic effects of nano-sized materials
… can exert epigenetic properties and there is increasing evidence of epigenetic deregulation
… performed so far to evaluate their potential epigenetic properties. Those studies highlight the …
… performed so far to evaluate their potential epigenetic properties. Those studies highlight the …
Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implications
JE Trosko, BV Madhukar, CC Chang - Life sciences, 1993 - Elsevier
… During normal development, the endogenous negatlve and positive extracellular signals …
mmght represent normal stem cells which were epigenetically, nongenetmcally, altered by our …
mmght represent normal stem cells which were epigenetically, nongenetmcally, altered by our …
Mitochondria, energetics, epigenetics, and cellular responses to stress
DT Shaughnessy, K McAllister, L Worth… - Environmental …, 2014 - ehp.niehs.nih.gov
… natural and synthetic compounds that exert their toxicity by a) altering mtDNA integrity, b) …
Research exploring the signaling associated with the DDR, epigenetics, and mitochondrial …
Research exploring the signaling associated with the DDR, epigenetics, and mitochondrial …
Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis
R Terranova, A Vitobello, ADR Espinola… - … Opinion in Toxicology, 2017 - Elsevier
… Enhancers are bound by regulatory transcription factors and integrate extracellular signalling
pathways with intracellular cell fate information to elicit cell type-specific transcriptional …
pathways with intracellular cell fate information to elicit cell type-specific transcriptional …
Genotoxic and epigenetic mechanisms in arsenic carcinogenicity
… epigenetic modifications have a role in arsenic-inducing adverse effects on human health.
The main epigenetic … the presence and consequences of these genetic/epigenetic alterations. …
The main epigenetic … the presence and consequences of these genetic/epigenetic alterations. …
Epigenetic effects induced by methamphetamine and methamphetamine‐dependent oxidative stress
F Limanaqi, S Gambardella, F Biagioni… - Oxidative medicine …, 2018 - Wiley Online Library
… into epigenetic events, which are derived from the translation of postsynaptic noncanonical
signaling … In the present section, we wish to mention that METH produces presynaptic toxicity …
signaling … In the present section, we wish to mention that METH produces presynaptic toxicity …
Genetic and epigenetic features in radiation sensitivity: Part I: cell signalling in radiation response
MH Bourguignon, PA Gisone, MR Perez… - European journal of …, 2005 - Springer
… hypersensitive to IR, with the benefit of decreased toxicity; furthermore, it is possible that local
… , has attracted greater attention to genetic and epigenetic susceptibility to cancer, possibly …
… , has attracted greater attention to genetic and epigenetic susceptibility to cancer, possibly …