In spite of the early speculation by Loewenstein that one of the critical distinguishing
phenotypes of cancers from normal cells was the dysfunction of gap junctional intercellular …

Some would argue that the search for the origin and treatment of this disease will continue
over the next quarter century in much the same manner as it has in the recent past, by adding …

… tional, and posttranslational levels (epigenetic toxicology). Both … field of toxicology is the
mechanism of chemically induced … The biological Rosetta Stone idea suggests that by looking at …

… In effect, epigenetic changes are alterations in the expression of genes at the … “epigenetic
changes” that can lead to heritable changes (which is correct). However, other epigenetic …

… These findings also are on the cutting edge of the field of "epigenetic toxicology" in that they
… Discovery of a Biological Rosetta Stone in the understanding of the cause and treatment of …

… /toxicology: study reports from all proof-ofconcept efficacy and safety/toxicology studies …
Conclusion: Envisioning the Rosetta Stone Stem cell research and application is opening great …

… of both the genetic and epigenetic factors during the in utero-perinatal developmental
period. Specifically, it will be assumed that the “epigenetic” component of carcinogenesis is the …

… the human genetics from a toxicological perspective. Notably, … , particularly from the epigenetic
viewpoint, remain largely … on the role of circRNA in toxicological research (ie, chemical …

… gene expression and epigenetic regulations were manifested … , epigenetic dysregulations
and transgenerational epigenetic inheritance induced by MXC, VIN, or other EDCs. Epigenetic …

… as epigenetic disruptors. We also discuss the advantages and challenges of using epigenetic
… risk assessment, and our perspectives on the future role of epigenetics in toxicology. …