Preserving human potential as freedom: a framework for regulating epigenetic harms
F Khan - Health Matrix, 2010 - HeinOnline
… Mapping human DNA did not turn out to be a Rosetta Stone unlocking the mysteries of heredity
… Lack of toxicological or material safety data is a problem that undermines many potential …
… Lack of toxicological or material safety data is a problem that undermines many potential …
A paradigm shift is required for the risk assessment of potential human health after exposure to low level chemical exposures: a response to the toxicity testing in the …
JE Trosko, BL Upham - International journal of toxicology, 2010 - journals.sagepub.com
… This challenge is not that mutations do not play roles in human-inherited or somatic diseases
but that chemical exposures bring about disease end points by epigenetic mechanisms or …
but that chemical exposures bring about disease end points by epigenetic mechanisms or …
Circular RNAs in toxicology
Y Shao, Y Jiang - Toxicological Sciences, 2021 - academic.oup.com
… the human genetics from a toxicological perspective. Notably, … , particularly from the epigenetic
viewpoint, remain largely … on the role of circRNA in toxicological research (ie, chemical …
viewpoint, remain largely … on the role of circRNA in toxicological research (ie, chemical …
Environmental Regulation of the Heart: The Role of Non-Coding RNA and Epigenetics in Influencing Mitochondrial and Cellular Health
QA Hathaway - 2019 - researchrepository.wvu.edu
… such as epigenetic modifications and promotion/inhibition of non-coding RNAs. Methods
and Results: We examined both acute stress to mitochondrial regulation (inhalation toxicology) …
and Results: We examined both acute stress to mitochondrial regulation (inhalation toxicology) …
[PDF][PDF] Pre-natal Epigenetic influences on acute and chronic diseases later in life, such as cancer: Global health crises resulting from a collision of biological and …
JE Trosko - Journal of Food Science and Nutrition, 2011 - Citeseer
… mechanisms, the primary cause is via “epigenetic”, or altered gene expression, modifications
… adult stem cells during early development by epigenetic chemicals could either increase or …
… adult stem cells during early development by epigenetic chemicals could either increase or …
Transgenerational toxicity induced by maternal AFB1 exposure in Caenorhabditis elegans associated with underlying epigenetic regulations
H Zhou, S Ren, Y Yang, Y Qin, T Guo, Y Zhou… - … Chemical Toxicology, 2024 - Elsevier
… Since epigenetic modifications need to pass through enough generations to exclude the …
elegans has been used as an important model animal in numerous toxicology and biological …
elegans has been used as an important model animal in numerous toxicology and biological …
[PDF][PDF] The role of epigenetics in the toxic effects induced by hexavalent chromium
… of epigenetic modification in the toxic effects of Cr(VI) and the association between ROS
and epigenetic … This review will illustrate the role of epigenetic modifications in Cr(VI)-induced …
and epigenetic … This review will illustrate the role of epigenetic modifications in Cr(VI)-induced …
Long noncoding RNAs: biogenesis, regulation, function, and their emerging significance in toxicology
S Choudhuri - Toxicology Mechanisms and Methods, 2023 - Taylor & Francis
… lncRNAs can modulate gene expression by various genetic and epigenetic mechanisms, such
… In chromatin modification, which is an epigenetic mechanism, lncRNAs function as part of …
… In chromatin modification, which is an epigenetic mechanism, lncRNAs function as part of …
[PDF][PDF] Precision Medicine for Childhood Cancers: Role of Epigenetics in Childhood Cancers”
JE Trosko - EC Paediatrics, 2017 - ecronicon.net
… of both the genetic and epigenetic factors during the in utero-perinatal developmental
period. Specifically, it will be assumed that the “epigenetic” component of carcinogenesis is the …
period. Specifically, it will be assumed that the “epigenetic” component of carcinogenesis is the …
[HTML][HTML] Epigenetic memories: structural marks or active circuits?
F Nicol-Benoît, P Le-Goff, Y Le-Dréan, F Demay… - Cellular and Molecular …, 2012 - Springer
… Epigenetic memory has also been involved in the delayed … -hormones, which have major
outcomes in toxicology [47–49]. … will not reveal some Rosetta stone of chromatin hieroglyphs. …
outcomes in toxicology [47–49]. … will not reveal some Rosetta stone of chromatin hieroglyphs. …