Noncoding RNA response to xenobiotic exposure: an indicator of toxicity and carcinogenicity

AK Marrone, FA Beland, IP Pogribny - … metabolism & toxicology, 2014 - Taylor & Francis
… by genetic and epigenetic changes, including altered expression of noncoding RNAs (ncRNAs).
While the effect of chemical carcinogens on genetic and epigenetic alterations and their …

[PDF][PDF] Evolving Concepts of Food Safety: The Need for Understanding Mechanisms of Food Toxicology for Public Policy

JE Trosko - crisis, 2018 - opastpublishers.com
… the prevention of acute diseases, the concept of epigenetics in food safety and food toxicology
is relatively new [72-76]. Since epigenetics or the regulation of gene expression is critical …

[图书][B] Preserving Brain Health in a Toxic Age: New Insights from Neuroscience, Integrative Medicine, and Public Health

AR Eiser - 2021 - books.google.com
… I also provide vignettes of selected neuroscientists and toxicologists who have provided
certain breakthroughs. This is a voyage of discovery into the science, history, and human …

[HTML][HTML] Human embryos, induced pluripotent stem cells, and organoids: models to assess the effects of environmental plastic pollution

D Miloradovic, D Pavlovic, MG Jankovic… - Frontiers in Cell and …, 2021 - frontiersin.org
… This distinction regarding the different toxicological effects on 2D and 3D cultures was
also confirmed in placental toxicity research. Accordingly, a recent study utilized scaffold-free …

Commentary on ''Toxicity Testing in the 21st Century: A vision and a Strategy'': Stem Cells and Cell-Cell Communication as Fundamental Targets in Assessing the …

JE Trosko - Human & experimental toxicology, 2010 - journals.sagepub.com
… induced oxidative stress-induced intra-cellular signaling to silence, transcriptionally, those
genes, then the surviving cell is not a mutant but has a phenotype shaped by an epigenetic

Embryonic atrazine exposure and later in life behavioral and brain transcriptomic, epigenetic, and pathological alterations in adult male zebrafish

KA Horzmann, LF Lin, B Taslakjian, C Yuan… - … biology and toxicology, 2021 - Springer
… It is possible that the epigenetic alterations observed at 72 hpf are corrected by maturity and
… with sex-specific effects, persistent epigenetic alterations might be present in and limited to …

[图书][B] Reproduction and adaptation: topics in human reproductive ecology

CGN Mascie-Taylor, L Rosetta - 2011 - books.google.com
In the space of one generation major changes have begun to take place in the field of human
reproduction. A rapid increase in the control of fertility and the understanding and treatment …

Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells

P Babica, R Zurabian, ER Kumar, R Chopra… - Toxicological …, 2016 - academic.oup.com
… gene expression and epigenetic regulations were manifested … , epigenetic dysregulations
and transgenerational epigenetic inheritance induced by MXC, VIN, or other EDCs. Epigenetic

Reflections on the use of 10 IARC carcinogenic characteristics for an objective approach to identifying and organizing results from certain mechanistic studies

JE Trosko - Toxicology Research and Application, 2017 - journals.sagepub.com
… It can be argued that epigenetic mechanisms might be the … in the genome, whereas an
epigenetic agent, while also could … These different cell types are epigenetically different and have …

[PDF][PDF] FINAL TECHNICAL REPORT" OXIDATIVE STRESS, SIGNAL TRANSDUCTION, CELL-CELL COMMUNICATION" F49620-95-1-0303

JE Trosko - apps.dtic.mil
… These finds also are on the cutting edge of the field of "epigenetic toxicology" in that they are
not only … Invited lecturer, "The discovery of the 'Biological Rosetta Stone': The role of cell-cell …