Noncoding RNA response to xenobiotic exposure: an indicator of toxicity and carcinogenicity
AK Marrone, FA Beland, IP Pogribny - … metabolism & toxicology, 2014 - Taylor & Francis
… by genetic and epigenetic changes, including altered expression of noncoding RNAs (ncRNAs).
While the effect of chemical carcinogens on genetic and epigenetic alterations and their …
While the effect of chemical carcinogens on genetic and epigenetic alterations and their …
[PDF][PDF] Evolving Concepts of Food Safety: The Need for Understanding Mechanisms of Food Toxicology for Public Policy
JE Trosko - crisis, 2018 - opastpublishers.com
… the prevention of acute diseases, the concept of epigenetics in food safety and food toxicology
is relatively new [72-76]. Since epigenetics or the regulation of gene expression is critical …
is relatively new [72-76]. Since epigenetics or the regulation of gene expression is critical …
[图书][B] Preserving Brain Health in a Toxic Age: New Insights from Neuroscience, Integrative Medicine, and Public Health
AR Eiser - 2021 - books.google.com
… I also provide vignettes of selected neuroscientists and toxicologists who have provided
certain breakthroughs. This is a voyage of discovery into the science, history, and human …
certain breakthroughs. This is a voyage of discovery into the science, history, and human …
[HTML][HTML] Human embryos, induced pluripotent stem cells, and organoids: models to assess the effects of environmental plastic pollution
D Miloradovic, D Pavlovic, MG Jankovic… - Frontiers in Cell and …, 2021 - frontiersin.org
… This distinction regarding the different toxicological effects on 2D and 3D cultures was
also confirmed in placental toxicity research. Accordingly, a recent study utilized scaffold-free …
also confirmed in placental toxicity research. Accordingly, a recent study utilized scaffold-free …
Commentary on ''Toxicity Testing in the 21st Century: A vision and a Strategy'': Stem Cells and Cell-Cell Communication as Fundamental Targets in Assessing the …
JE Trosko - Human & experimental toxicology, 2010 - journals.sagepub.com
… induced oxidative stress-induced intra-cellular signaling to silence, transcriptionally, those
genes, then the surviving cell is not a mutant but has a phenotype shaped by an epigenetic …
genes, then the surviving cell is not a mutant but has a phenotype shaped by an epigenetic …
Embryonic atrazine exposure and later in life behavioral and brain transcriptomic, epigenetic, and pathological alterations in adult male zebrafish
KA Horzmann, LF Lin, B Taslakjian, C Yuan… - … biology and toxicology, 2021 - Springer
… It is possible that the epigenetic alterations observed at 72 hpf are corrected by maturity and
… with sex-specific effects, persistent epigenetic alterations might be present in and limited to …
… with sex-specific effects, persistent epigenetic alterations might be present in and limited to …
[图书][B] Reproduction and adaptation: topics in human reproductive ecology
CGN Mascie-Taylor, L Rosetta - 2011 - books.google.com
In the space of one generation major changes have begun to take place in the field of human
reproduction. A rapid increase in the control of fertility and the understanding and treatment …
reproduction. A rapid increase in the control of fertility and the understanding and treatment …
Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells
P Babica, R Zurabian, ER Kumar, R Chopra… - Toxicological …, 2016 - academic.oup.com
… gene expression and epigenetic regulations were manifested … , epigenetic dysregulations
and transgenerational epigenetic inheritance induced by MXC, VIN, or other EDCs. Epigenetic …
and transgenerational epigenetic inheritance induced by MXC, VIN, or other EDCs. Epigenetic …
Reflections on the use of 10 IARC carcinogenic characteristics for an objective approach to identifying and organizing results from certain mechanistic studies
JE Trosko - Toxicology Research and Application, 2017 - journals.sagepub.com
… It can be argued that epigenetic mechanisms might be the … in the genome, whereas an
epigenetic agent, while also could … These different cell types are epigenetically different and have …
epigenetic agent, while also could … These different cell types are epigenetically different and have …
[PDF][PDF] FINAL TECHNICAL REPORT" OXIDATIVE STRESS, SIGNAL TRANSDUCTION, CELL-CELL COMMUNICATION" F49620-95-1-0303
JE Trosko - apps.dtic.mil
… These finds also are on the cutting edge of the field of "epigenetic toxicology" in that they are
not only … Invited lecturer, "The discovery of the 'Biological Rosetta Stone': The role of cell-cell …
not only … Invited lecturer, "The discovery of the 'Biological Rosetta Stone': The role of cell-cell …