… We argue here that in prostate cancer epigenetic mechanisms … We will therefore discuss
in turn altered DNA methylation, … , for which the evidence in prostate cancer is scarce [19]. …

… in human prostate cancer. We will also discuss the potential involvement of DNA methylation
in age-related, … DNA methylation is an epigenetic event that affects cell function by altering …

… , epigenetic changes are reversible and occur very rapidly. The major epigenetic mechanisms
include DNA methylation, … changes in gene expression caused by microRNAs (miRNAs). …

… Long-range epigenetic activation and repression is a phenomenon in which large regions …
repressed in PCa due to concordant epigenetic changes, such as histone modification or DNA …

… Epigenetic mechanisms such as DNA methylation and histone modification play an … alterations
associated with the development and progression of prostate cancer [4, 5]. In mammalian …

… nature of DNA methylation, its general role in cancer and the … surrounding DNA methylation
as relating to prostate cancer. … the epigenetic and genetic changes in prostate cancer. …

… hypermethylated in prostate cancers, more than 40 genes have been reported to be targets
of DNA hypermethylation-associated epigenetic gene silencing in prostate cancer cells (5). …

… Altered DNA methylation, changes in the expression of … for prostate cancer detection and
classification. The reversible nature of DNA methylation forms the basis of epigenetic cancer …

… DNA methylation is the best-established epigenetic mark that is critical for the allele-specific
expression of imprinted genes [49]. Hypomethylation of specific chromosomal domains has …

… the effect of DNA methylation on gene expression. In this study, we focus on prostate cancer,
but the observed relations between DNA hypermethylation and gene expression are likely …