… from a cancer-free region of the matched PCa patient, we cannot rule out that epigenomic
… Altogether, our study points to an important role of the epigenome in mediating or facilitating …

… of the cancer cell clones and to their acquisition of critical somatic genome and epigenomic
… This review aims to provide an overview about the genetic and epigenetic alterations having …

… development, and inhibitors targeting these epigenomic aberrations might be novel … overview
of epigenetic alterations in the development and progression of prostate cancer, focusing …

… Changes in DNA methylation, the major DNA marks of somatic epigenome alterations,
constitute a superb source of cancer biomarkers for several reasons. For one, such changes can …

… in advanced prostate cancer. Prostate cancer follows aberrant epigenetic alterations that …
DNA methylation and deacetylation whereas a prostate cancer cell is characterised by tumour …

… of cancer deaths in men in France. Apart from the genetic alterations in prostate cancer, …
In this review, we summarized epigenetic mechanisms in prostate cancer. Epigenetic drugs …

… the dependency of prostate cancer cells on androgens may shape the epigenome, beyond
individual … Because of their crucial role, epigenetic alterations may become highly useful for …

… Another way to take advantage of epigenetic alterations occurring in prostate cancer is to
determine whether changes in microRNA profiles represent diagnosis biomarkers or are …

… required before the cancer epigenome can be … in prostate cancer and discuss the clinical
potential of cancer epigenetics for the diagnosis and treatment of this disease. Prostate cancer …

… Various aspects of the epigenome have also been … the epigenome and to highlight their
translational potential as functional biomarkers. To this end, exploration of TCGA prostate cancer …