… and myofibroblasts with resident lung epithelial cells has become increasingly clear. We …
orchestrating the pro-fibrotic interactions of epithelial cells and fibroblasts in their “fibrosis of two”…

… , and Notch pathways in adult epithelial cell plasticity and pulmonary fibrosis. In contrast, …
of how or whether such epithelial cells directly interact with interstitial fibroblasts to lead to …

… activation of alveolar epithelial cells in idiopathic pulmonary fibrosis. The present … epithelial
cell injury can lead to fibroblast recruitment and accumulation in idiopathic pulmonary fibrosis…

… of bleomycin on lung epithelial cells and susceptibility to pulmonary fibrosis are well described
in … [170] PGE 2 is secreted by lung epithelial cells and lung fibroblasts, suggesting that …

… ship between epithelial cells and fibroblasts that may affect epithelial cell function. During
lung development, a fibroblast-derived factor, … pulmonary fibrosis after 10 days.11 In this study, …

… the epithelium and fibroblasts and other resident cells have … of epithelial cells and the
mechanisms underlying the fibrotic … a bidirectional interaction enhancing a fibrotic response [72]. …

… The mechanisms and mediators linking epithelial cell dysfunction to tissue fibrosis have not
… to lung fibrosis. First, TGF-β has diverging effects on the epithelial and fibroblast proliferative …

… the fibrosing lung, the lung becomes stiffer, making it easier for any degree of epithelial cell
… epithelial cells overlying regions of lung fibrosis (11), an effect we have consistently seen in …

… through their close interaction with the injured alveolar epithelium. The vast array … pulmonary
fibrosis we hypothesize that such fibrotic changes will involve both epithelial and fibroblast-…

… Second, epithelial cell damage and perturbation of epithelial-fibroblast interactions is … in
IPF, an initial epithelial cell injury and activation induces fibroblast migration/proliferation and …