Cellular responses to viral infection in humans: lessons from Epstein-Barr virus

AD Hislop, GS Taylor, D Sauce… - Annu. Rev. Immunol …, 2007 - annualreviews.org
… As with the much larger CD8 response, virus-specific CD4 + T … , responses to lytic and latent
antigens decline rapidly in a matter of weeks (32) and numbers of CD4 + T cells responding

Antibody response to Epstein-Barr virus in infectious mononucleosis

J Nikoskelainen, P Hänninen - Infection and Immunity, 1975 - Am Soc Microbiol
… Altogether 171 serum specimens from 58 patients with heterophil antibodypositive infectious
mononucleosis were studied for antibody response to EpsteinBarr virus (EBV). The sera …

Rapid antibody responses to Epstein-Barr virus correlate with reduced severity of primary infection

JM Geris, AL Stancari, MR Meirhaeghe… - Journal of Clinical …, 2022 - Elsevier
Background We investigated Epstein-Barr virus (EBV) antibody kinetics in university freshmen
who developed laboratory-documented primary EBV infection during prospective studies …

Three pathways of Epstein-Barr virus gene activation from EBNA1-positive latency in B lymphocytes

M Rowe, AL Lear, D Croom-Carter, AH Davies… - Journal of …, 1992 - Am Soc Microbiol
… lymphoma lines responding to anti-immunoglobulin treatment revealed three response
pathways of EBV gene activation from EBNAl-positive latency. A first, rapid response pathway …

Stimulus duration and response time independently influence the kinetics of lytic cycle reactivation of Epstein-Barr virus

J Countryman, L Gradoville… - Journal of …, 2009 - Am Soc Microbiol
… The response time is strongly influenced by the virus/cell background. A very rapid response
was observed in Akata cells (Fig. 10). This rapid response in Akata cells may be influenced …

Primary epstein-barr virus infection

SK Dunmire, PS Verghese, HH Balfour Jr - Journal of Clinical Virology, 2018 - Elsevier
… system was an understudied aspect of the overall immune response during infectious
mononucleosis. In patients presenting with infectious mononucleosis, a decrease in the number of …

Host factors associated with the kinetics of EpsteinBarr virus DNA load in patients with primary EpsteinBarr virus infection

H Nakai, Y Kawamura, K Sugata… - Microbiology and …, 2012 - Wiley Online Library
… in the rapid than in the slow regression group in the present study, the innate immune response
… significantly higher concentrations of these in the rapid than the slow regression group. …

Detection of EpsteinBarr viral DNA in serum using rapid-cycle PCR

CL Mouritsen, CT Wittwer, G Reed, TM Khan… - … and molecular medicine, 1997 - Elsevier
… One objective of this study was to determine if nested, rapid-cycle DNA amplification can
be … mononucleosis by using recombinant Eprologic responses. In conclusion, nested rapid-…

EpsteinBarr Virus

BC Gärtner, J Preiksaitis - Manual of clinical microbiology, 2015 - Wiley Online Library
… combine high sensitivity and specificity with rapid detection are currently available. Antibody
… to prevent and diagnose disease and to monitor response to therapy. In most of these …

Epstein-Barr virus—recent advances

KF Macsween, DH Crawford - The Lancet infectious diseases, 2003 - thelancet.com
EpsteinBarr virus is a tumorigenic herpes virus that is ubiquitous in the adult … mononucleosis
in roughly 50% of cases. More than 90% of the world's population carry EpsteinBarr virus …