Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer

M Campbell-Thompson, IJ Lynch, B Bhardwaj - Cancer research, 2001 - AACR
ERβ isoforms in colon tumors, normal colonic mucosa, and colon cancer cell lines. ERαand
… For these reasons, we propose that ERβ may mediate estrogenic effects on colon cancer

Functional estrogen receptor β in colon cancer cells

G Fiorelli, L Picariello, V Martineti, F Tonelli… - Biochemical and …, 1999 - Elsevier
… In addition, [3H]17 -estradiol (17 E2) binding to intact colon cancer cells was evaluated.
RT-… ER in the four colon cancer cell lines. Conversely, wild-type ER isoform 1 was highly …

ERβ isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates

NACS Wong, RDG Malcomson… - The Journal of …, 2005 - Wiley Online Library
… and therefore only nuclear expression of each isoform was assessed. To … ERβ in CRC 29,
30, absence of ERβ isoform expression was defined as staining of less than 10% of carcinoma

Expression of estrogen receptor β in colon cancer progression

F Castiglione, A Taddei… - Diagnostic Molecular …, 2008 - journals.lww.com
… The aim of the present study was to assess the importance of ERβ and its isoforms β1, β2,
and β5 in colon adenocarcinoma by investigating its mRNA expression levels in a well-…

[HTML][HTML] Expression of estrogen receptor β in human colorectal cancer

LQ Xie, JP Yu, HS Luo - World Journal of Gastroenterology, 2004 - ncbi.nlm.nih.gov
… Up to now, several ERβ isoforms have been identified such as ERβ1, … ERβ isoforms is still
unknown. Meanwhile, published data about the expression of ERα and ERβ in colon cancer

Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation

PA Konstantinopoulos, A Kominea, G Vandoros… - … journal of cancer, 2003 - Elsevier
… the expression of ERβ in both normal colonic wall and colon cancer. ERβ expression
was … exist [15] and the monoclonal antibody employed in this study recognises isoforms 1–3. …

[HTML][HTML] ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components

V Martineti, L Picariello, I Tognarini… - … -related cancer, 2005 - erc.bioscientifica.com
… This situation is further complicated by the complexity of species and isoform distribution
of ERs, with consequent ligand tissue-specificity and by their low expression levels in …

[HTML][HTML] Estrogen receptors and their implications in colorectal carcinogenesis

F Caiazza, EJ Ryan, G Doherty, DC Winter… - Frontiers in …, 2015 - frontiersin.org
… However, during colon cancer progression, ERβ expression is lost, suggesting that … subset
of patients with decreased ERβ loss or differential expression of ERβ isoforms, in order to help …

[HTML][HTML] Role of ERβ palmitoylation in the inhibition of human colon cancer cell proliferation

P Galluzzo, F Caiazza, S Moreno… - … -related cancer, 2007 - erc.bioscientifica.com
… Here, using colon cancer cells which contain only one ERβ isoform, we demonstrated that
ERβ is localized to the plasma membrane and originate rapid signal transduction cascades …

[HTML][HTML] Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer

PR Stevanato Filho, S Aguiar Junior, MD Begnami… - BMC cancer, 2017 - Springer
… Thus, we investigated mRNA expression of ERβ isoforms in normal mucosa and polyps. …
expression levels of ERβ isoforms are downregulated in sporadic colorectal cancer and in FAP …