Expression of estrogen receptor (ER) subtypes and ERβ isoforms in colon cancer
M Campbell-Thompson, IJ Lynch, B Bhardwaj - Cancer research, 2001 - AACR
… ERβ isoforms in colon tumors, normal colonic mucosa, and colon cancer cell lines. ERαand
… For these reasons, we propose that ERβ may mediate estrogenic effects on colon cancer …
… For these reasons, we propose that ERβ may mediate estrogenic effects on colon cancer …
Functional estrogen receptor β in colon cancer cells
G Fiorelli, L Picariello, V Martineti, F Tonelli… - Biochemical and …, 1999 - Elsevier
… In addition, [3H]17 -estradiol (17 E2) binding to intact colon cancer cells was evaluated.
RT-… ER in the four colon cancer cell lines. Conversely, wild-type ER isoform 1 was highly …
RT-… ER in the four colon cancer cell lines. Conversely, wild-type ER isoform 1 was highly …
ERβ isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates
NACS Wong, RDG Malcomson… - The Journal of …, 2005 - Wiley Online Library
… and therefore only nuclear expression of each isoform was assessed. To … ERβ in CRC 29,
30, absence of ERβ isoform expression was defined as staining of less than 10% of carcinoma …
30, absence of ERβ isoform expression was defined as staining of less than 10% of carcinoma …
Expression of estrogen receptor β in colon cancer progression
F Castiglione, A Taddei… - Diagnostic Molecular …, 2008 - journals.lww.com
… The aim of the present study was to assess the importance of ERβ and its isoforms β1, β2,
and β5 in colon adenocarcinoma by investigating its mRNA expression levels in a well-…
and β5 in colon adenocarcinoma by investigating its mRNA expression levels in a well-…
[HTML][HTML] Expression of estrogen receptor β in human colorectal cancer
LQ Xie, JP Yu, HS Luo - World Journal of Gastroenterology, 2004 - ncbi.nlm.nih.gov
… Up to now, several ERβ isoforms have been identified such as ERβ1, … ERβ isoforms is still
unknown. Meanwhile, published data about the expression of ERα and ERβ in colon cancer …
unknown. Meanwhile, published data about the expression of ERα and ERβ in colon cancer …
Oestrogen receptor beta (ERβ) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation
PA Konstantinopoulos, A Kominea, G Vandoros… - … journal of cancer, 2003 - Elsevier
… the expression of ERβ in both normal colonic wall and colon cancer. ERβ expression
was … exist [15] and the monoclonal antibody employed in this study recognises isoforms 1–3. …
was … exist [15] and the monoclonal antibody employed in this study recognises isoforms 1–3. …
[HTML][HTML] ERβ is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components
V Martineti, L Picariello, I Tognarini… - … -related cancer, 2005 - erc.bioscientifica.com
… This situation is further complicated by the complexity of species and isoform distribution
of ERs, with consequent ligand tissue-specificity and by their low expression levels in …
of ERs, with consequent ligand tissue-specificity and by their low expression levels in …
[HTML][HTML] Estrogen receptors and their implications in colorectal carcinogenesis
… However, during colon cancer progression, ERβ expression is lost, suggesting that … subset
of patients with decreased ERβ loss or differential expression of ERβ isoforms, in order to help …
of patients with decreased ERβ loss or differential expression of ERβ isoforms, in order to help …
[HTML][HTML] Role of ERβ palmitoylation in the inhibition of human colon cancer cell proliferation
… Here, using colon cancer cells which contain only one ERβ isoform, we demonstrated that
ERβ is localized to the plasma membrane and originate rapid signal transduction cascades …
ERβ is localized to the plasma membrane and originate rapid signal transduction cascades …
[HTML][HTML] Oestrogen receptor beta isoform expression in sporadic colorectal cancer, familial adenomatous polyposis and progressive stages of colorectal cancer
PR Stevanato Filho, S Aguiar Junior, MD Begnami… - BMC cancer, 2017 - Springer
… Thus, we investigated mRNA expression of ERβ isoforms in normal mucosa and polyps. …
expression levels of ERβ isoforms are downregulated in sporadic colorectal cancer and in FAP …
expression levels of ERβ isoforms are downregulated in sporadic colorectal cancer and in FAP …