Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation
IA Elsum, C Martin, PO Humbert - Journal of cell science, 2013 - journals.biologists.com
… , lack tight junctions under standard tissue culture conditions (… the formation of functional
tight junctions. We provide evidence for a pathway in which Scribble regulates MAPK-ERK …
tight junctions. We provide evidence for a pathway in which Scribble regulates MAPK-ERK …
The involvement of the ERK-MAPK pathway in TGF-β1–mediated connexin43-gap junction formation in chondrocytes
Q Wang, C Zhou, D Zhang, J Zou, W Liu… - Connective Tissue …, 2019 - Taylor & Francis
… Furthermore, the inhibitor of ERK attenuated the increases of Cx43 expressions and
functional gap junction formations induced by TGF-β1, while cross-talk between ERK-MAPK and …
functional gap junction formations induced by TGF-β1, while cross-talk between ERK-MAPK and …
Essential role of the ERK/MAPK pathway in blood-placental barrier formation
V Nadeau, J Charron - Development, 2014 - journals.biologists.com
… formation. Map2k1 +/− Map2k2 +/− mutants show reduced vascularization of the labyrinth and
defective formation … To define the cell type-specific contribution of the ERK/MAPK pathway …
defective formation … To define the cell type-specific contribution of the ERK/MAPK pathway …
Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells
Y Wang, J Zhang, X Yi, XY Fu-Shin - Experimental eye research, 2004 - Elsevier
… the MAPK signaling pathway plays a key role in the formation and … ERK MAP kinase
signaling and increase TJ permeability, PKC may play a role in the activation of ERK MAP kinase …
signaling and increase TJ permeability, PKC may play a role in the activation of ERK MAP kinase …
Restoration of E-cadherin cell-cell junctions requires both expression of E-cadherin and suppression of ERK MAP kinase activation in Ras-transformed breast …
Q Li, RR Mattingly - Neoplasia, 2008 - Elsevier
… prevent the formation of functional E-cadherin junctions by preventing the appropriate subcellular
localization of E-cadherin. We have found that inhibition of ERK MAPK activation is …
localization of E-cadherin. We have found that inhibition of ERK MAPK activation is …
Inhibition of ERK‐MAP kinase signaling by RSK during Drosophila development
… to an enhanced ERK‐dependent cellular differentiation such as ectopic photoreceptor‐ and
vein‐cell formation. Conversely, overexpression of RSK dramatically suppressed the ERK‐…
vein‐cell formation. Conversely, overexpression of RSK dramatically suppressed the ERK‐…
The MAPK/ERK-signaling pathway regulates the expression and distribution of tight junction proteins in the mouse proximal epididymis
B Kim, S Breton - Biology of reproduction, 2016 - academic.oup.com
… We examine here the role of the MAPK/ERK1/2 pathway in the regulation of TJ proteins in
… the MAPK/ERK1/2 pathway in the regulation of cell-cell events that control the formation and …
… the MAPK/ERK1/2 pathway in the regulation of cell-cell events that control the formation and …
Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway
… formation of TJs during epithelial cellular polarization. At the initial stage of cell–cell contact
of epithelial cells, primordial spot-like junctions are formed … line that MAPK/ERK pathway has …
of epithelial cells, primordial spot-like junctions are formed … line that MAPK/ERK pathway has …
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis
G Mavria, Y Vercoulen, M Yeo, H Paterson… - Cancer cell, 2006 - cell.com
… Temporal and spatial modulation of Rho GTPases during in vitro formation of capillary
vascular network. Adherens junctions and myosin light chain as targets of Rac1 and RhoA. …
vascular network. Adherens junctions and myosin light chain as targets of Rac1 and RhoA. …
Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathway
Z Lu, L Ding, H Hong, J Hoggard, Q Lu… - Experimental cell research, 2011 - Elsevier
… inhibitor of ERK/MAPK pathway, was able to block the motile effect. Claudin-7 formed stable
complexes with claudin-1 and -3 and was able to recruit them to the cell-cell junction area in …
complexes with claudin-1 and -3 and was able to recruit them to the cell-cell junction area in …
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