Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …
TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… A phase 3 clinical trial compared erlotinib alone with erlotinib plus bevacizumab in patients
who had disease progression after platinum-based therapy. In that trial, patients were not …
who had disease progression after platinum-based therapy. In that trial, patients were not …
Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …
H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… of erlotinib plus bevacizumab with erlotinib alone in patients … patients given bevacizumab
and erlotinib had improved progression-free survival compared with patients given erlotinib …
and erlotinib had improved progression-free survival compared with patients given erlotinib …
[HTML][HTML] Randomized, phase III trial of figitumumab in combination with erlotinib versus erlotinib alone in patients with nonadenocarcinoma nonsmall-cell lung cancer
… This multicenter, randomized, phase III study investigated the efficacy of figitumumab plus
erlotinib compared with erlotinib alone in patients with pretreated, nonsmall-cell lung cancer (…
erlotinib compared with erlotinib alone in patients with pretreated, nonsmall-cell lung cancer (…
Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer
EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… by RECIST 1.0 in the erlotinib plus fulvestrant arm versus erlotinib alone arm. Secondary …
identification of patient subgroups that are distinct with respect to response. Patients were …
identification of patient subgroups that are distinct with respect to response. Patients were …
Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567) …
T Seto, T Kato, M Nishio, K Goto, S Atagi… - The lancet …, 2014 - thelancet.com
… With use of EGFR tyrosine-kinase inhibitor monotherapy for patients with activating EGFR
… combination of erlotinib and bevacizumab compared with erlotinib alone in patients with non…
… combination of erlotinib and bevacizumab compared with erlotinib alone in patients with non…
Erlotinib plus bevacizumab (EB) versus erlotinib alone (E) as first-line treatment for advanced EGFR mutation–positive non-squamous non–small-cell lung cancer …
N Yamamoto, T Seto, M Nishio, K Goto, I Okamoto… - 2018 - ascopubs.org
… (PFS) in patients with NSCLC with activating EGFR mutation compared with E alone. Overall
… We conducted survival follow-up of the patients in JO25567. Methods: JO25567 was open-…
… We conducted survival follow-up of the patients in JO25567. Methods: JO25567 was open-…
Erlotinib (Tarceva): an update on the clinical trial program
RS Herbst - Seminars in oncology, 2003 - Elsevier
… Phase III trials with erlotinib in non-small cell lung cancer and … to optimize the use of erlotinib
alone and in combination with … The two studies of erlotinib in patients with advanced solid …
alone and in combination with … The two studies of erlotinib in patients with advanced solid …
Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer
DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
… to erlotinib in patients with relapsed NSCLC. Although PFS was improved with the combination
compared with erlotinib alone (… , and RET, with erlotinib in patients with relapsed NSCLC …
compared with erlotinib alone (… , and RET, with erlotinib in patients with relapsed NSCLC …
… MetLung trial: a randomized, double-blind phase iii study of onartuzumab (MetMAb) in combination with erlotinib versus erlotinib alone in patients who have received …
DR Spigel, MJ Edelman, T Mok, K O'Byrne… - Clinical Lung Cancer, 2012 - Elsevier
… with erlotinib compared with erlotinib alone, as second- or third-line treatment, in patients …
Approximately 490 patients (245 per treatment arm) will receive erlotinib (150 mg oral daily) …
Approximately 490 patients (245 per treatment arm) will receive erlotinib (150 mg oral daily) …
Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma …
PA Jänne, X Wang, MA Socinski, J Crawford… - Journal of clinical …, 2012 - ascopubs.org
… of erlotinib alone or in combination with chemotherapy in patients with these characteristics.
… We thus developed a randomized phase II trial to investigate the efficacy of erlotinib alone …
… We thus developed a randomized phase II trial to investigate the efficacy of erlotinib alone …
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