Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
Importance Erlotinib is a standard first-line therapy for patients with epidermal growth factor
receptor (EGFR)–mutant non–small cell lung cancer (NSCLC). Median progression-free …

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… compare the efficacy of erlotinib plus bevacizumab with erlotinib alone in patients with EGFR…
and erlotinib had improved progression-free survival compared with patients given erlotinib

Chemotherapy plus erlotinib versus chemotherapy alone for treating advanced non-small cell lung cancer: a meta-analysis

JL Xu, B Jin, ZH Ren, YQ Lou, ZR Zhou, QZ Yang… - PloS one, 2015 - journals.plos.org
… with pemetrexed alone [17]. This intercalated therapy avoided the G1 arrest by erlotinib, thus
… In this meta-analysis, continuous erlotinib plus chemotherapy versus chemotherapy alone

Erlotinib in lung cancer—molecular and clinical predictors of outcome

MS Tsao, A Sakurada, JC Cutz, CQ Zhu… - … England Journal of …, 2005 - Mass Medical Soc
erlotinib with a placebo for non–small-cell lung cancer demonstrated a survival benefit for
erlotinib… trial to investigate whether responsiveness to erlotinib and its impact on survival were …

Chemotherapy with erlotinib or chemotherapy alone in advanced non‐small cell lung cancer with acquired resistance to EGFR tyrosine kinase inhibitors

SB Goldberg, GR Oxnard, S Digumarthy… - The …, 2013 - academic.oup.com
… A study by the Cancer and Leukemia Group B found that the addition of carboplatin and … to
first‐line erlotinib was no better than erlotinib alone in never/light smokers with advanced lung

Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer

DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
… ) phase III trial, bevacizumab was added to erlotinib in patients with relapsed NSCLC.
Although PFS was improved with the combination compared with erlotinib alone (HR, 0.62; P < .…

Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double …

RS Herbst, R Ansari, F Bustin, P Flynn, L Hart… - The Lancet, 2011 - thelancet.com
… Bevacizumab and erlotinib target different tumour growth pathways with little overlap in their
… activity of erlotinib plus bevacizumab for recurrent or refractory non-small-cell lung cancer (…

[HTML][HTML] Randomized, phase III trial of figitumumab in combination with erlotinib versus erlotinib alone in patients with nonadenocarcinoma nonsmall-cell lung cancer

GV Scagliotti, I Bondarenko, F Blackhall, F Barlesi… - Annals of …, 2015 - Elsevier
… This multicenter, randomized, phase III study investigated the efficacy of figitumumab plus
erlotinib compared with erlotinib alone in patients with pretreated, nonsmall-cell lung cancer (…

Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567) …

T Seto, T Kato, M Nishio, K Goto, S Atagi… - The lancet …, 2014 - thelancet.com
… EGFR mutation-positive non-small-cell lung cancer (NSCLC), median progression-free …
the combination of erlotinib and bevacizumab compared with erlotinib alone in patients with …

Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non–small-cell lung cancer: a phase III trial

GV Scagliotti, M Krzakowski, A Szczesna… - Journal of clinical …, 2012 - ascopubs.org
erlotinib may enhance antitumor activity compared with either agent alone in non–small-cell
lung cancer (… plus erlotinib versus placebo plus erlotinib in patients with refractory NSCLC. …