Effect of erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
erlotinib and bevacizumab superior to erlotinib alone to treat epidermal growth factor receptor
(EGFR)–mutant non–small cell lung cancererlotinib alone, the combination of erlotinib and …

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… compare the efficacy of erlotinib plus bevacizumab with erlotinib alone in patients with EGFR…
and erlotinib had improved progression-free survival compared with patients given erlotinib

Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer

DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
… Sorafenib, an oral multikinase inhibitor, has shown preliminary activity in non–small-cell lung
cancer (NSCLC). Patients with advanced NSCLC were treated with erlotinib with or without …

Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double …

RS Herbst, R Ansari, F Bustin, P Flynn, L Hart… - The Lancet, 2011 - thelancet.com
… Bevacizumab and erlotinib target different tumour growth pathways with little overlap in their
… activity of erlotinib plus bevacizumab for recurrent or refractory non-small-cell lung cancer (…

Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non–small-cell lung cancer: a phase III trial

GV Scagliotti, M Krzakowski, A Szczesna… - Journal of clinical …, 2012 - ascopubs.org
erlotinib may enhance antitumor activity compared with either agent alone in non–small-cell
lung cancer (NSCLC), based on the importance of the signaling pathways involved in tumor

Antitumor activity of erlotinib (OSI-774, Tarceva) alone or in combination in human non-small cell lung cancer tumor xenograft models

B Higgins, K Kolinsky, M Smith, G Beck… - Anti-cancer …, 2004 - journals.lww.com
… inhibitor erlotinib in athymic nude mice bearing non-small cell lung cancer (NSCLC) xenograft
models. Immunohistochemistry determined the HER1/EGFR status of the NSCLC tumor

Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non–small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial

U Gatzemeier, A Pluzanska, A Szczesna… - Journal of Clinical …, 2007 - ascopubs.org
… vomiting 32,33 ) is distinct from that of erlotinib. Here we report the results of a phase … (Tarceva
Lung Cancer Investigation [TALENT]) of cisplatin and gemcitabine with or without erlotinib

… of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non–small-cell lung cancer

RS Herbst, VJ O'Neill, L Fehrenbacher… - Journal of Clinical …, 2007 - ascopubs.org
… growth factor monoclonal antibody, and erlotinib, a reversible, orally available … of non–small-cell
lung cancer (NSCLC). A single-arm phase I and II study of bevacizumab plus erlotinib

Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians

Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
… Inhibition of epidermal growth factor receptor (EGFR) has become an important target in the
treatment of advanced non-small cell lung cancer (NSCLC). Erlotinib and gefitinib, two small

Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567) …

T Seto, T Kato, M Nishio, K Goto, S Atagi… - The lancet …, 2014 - thelancet.com
… activating EGFR mutation-positive non-small-cell lung cancer (NSCLC), median progression…
the combination of erlotinib and bevacizumab compared with erlotinib alone in patients with …