… growth factor receptor mutated non-small cell lung cancer using different tyrosine kinase inhibitors in The Netherlands: a retrospective, nationwide registry study

RGP Gijtenbeek, RAM Damhuis… - The Lancet Regional …, 2023 - thelancet.com
… to the first-generation TKI erlotinib or gefitinib in the FLAURA study. In a post hoc analysis,
a … I BLOOM trial as upfront treatment (n = 41) and in a recent retrospective multi-center study

A retrospective study of the efficacy of combined EGFR‑TKI plus VEGF inhibitor/cytotoxic therapy vs. EGFR‑TKI monotherapy for PD‑L1‑positive EGFR‑mutant non …

M Inomata, Y Kawashima, R Saito… - Oncology …, 2023 - spandidos-publications.com
… The present multicenter studyerlotinib plus VEGF inhibitors and gefitinib plus cytotoxic
agents, compared with first-generation EGFR-TKI monotherapy. The NEJ026 trial, a phase 3 trial, …

Erlotinib has better efficacy than gefitinib in adenocarcinoma patients without EGFR-activating mutations, but similar efficacy in patients with EGFR-activating …

WS Wu, YM Chen, CM Tsai… - Experimental and …, 2012 - spandidos-publications.com
trial to date, which compares gefitinib and erlotinib treatment, not to mention a study
performed based on the tumor EGFR mutation status. In the present study, we retrospectively

Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations

W Liang, X Wu, W Fang, Y Zhao, Y Yang, Z Hu, C Xue… - PloS one, 2014 - journals.plos.org
study indicated that erlotinib, gefitinib, afatinib and icotinib shared equivalent efficacy but
presented different efficacy-toxicity pattern for EGFR-mutated patients. Erlotinibretrospective

Icotinib is an active treatment of non-small-cell lung cancer: a retrospective study

X Chen, Q Zhu, Y Liu, P Liu, Y Yin, R Guo, K Lu, Y Gu… - PloS one, 2014 - journals.plos.org
… in gefitinib and erlotinib studies, the PFS and OS in this study … However, one should note
that this is a retrospective study … the abovementioned studies on gefitinib and erlotinib were all …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - Cancer Research and …, 2019 - ncbi.nlm.nih.gov
… This retrospective population-based study included patients with NSCLC who received first-line
afatinib, gefitinib, or erlotinib … are known to be resistant to afatinib, gefitinib, and erlotinib. …

Gefitinib is of more benefit in chemotherapy-naive patients with good performance status and adenocarcinoma histology: retrospective analysis of 575 Korean patients

DH Lee, JY Han, HT Kim, JS Lee - Lung Cancer, 2006 - Elsevier
… We analyzed retrospectively 575 NSCLC patients treated with gefitinib to identify … gefitinib
therapy but also to conduct future prospective clinical studies, including translational studies

Predictors of outcome for patients with lung adenocarcinoma carrying the epidermal growth factor receptor mutation receiving 1st-line tyrosine kinase inhibitors …

S Pilotto, M Di Maio, U Peretti, S Kinspergher… - Critical Reviews in …, 2014 - Elsevier
… mixed) and to trial design (retrospective versus prospective EGFR analysis), was found; a
trend toward significance with regard to type of drug (gefitinib versus erlotinib versus afatinib) …

Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… MST compared with gefitinib and icotinib (P<0.05). In conclusion, gefitinib, erlotinib and
icotinib … However, gefitinib resulted in a lower frequency of fatigue, and nausea and vomiting, …

Which is better EGFR-TKI followed by osimertinib: afatinib or gefitinib/erlotinib?

M Tamiya, A Tamiya, H Suzuki, K Moriizumi… - … Research, 2019 - ar.iiarjournals.org
… We conducted a multicenter retrospective study across three medical centers in Japan.
The study design and methodology was approved by the Institutional Review Board of each …