Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
… Yeo reduced the dose of erlotinib down to 25 mg/day in a retrospective study and achieved
a similar or even better prognosis compared with the standard dose. [67] Similar results were …

[HTML][HTML] Apatinib plus gefitinib as first-line treatment in advanced EGFR-mutant NSCLC: the phase III ACTIVE study (CTONG1706)

H Zhao, W Yao, X Min, K Gu, G Yu, Z Zhang… - Journal of Thoracic …, 2021 - Elsevier
… first-generation EGFR TKIs (eg, gefitinib and erlotinib) is approximately 10 to 12 months.10, …
, is a superior first-line therapy according to the FLAURA study, 11 , 12 there is no standard …

Comparing the effects of afatinib with gefitinib or Erlotinib in patients with advanced-stage lung adenocarcinoma harboring non-classical epidermal growth factor …

YC Shen, GC Tseng, CY Tu, WC Chen, WC Liao… - Lung Cancer, 2017 - Elsevier
… No study has compared these two generations of EGFR-TKIs in this patient population.
Herein, we conducted a retrospective study to assess the efficacy of gefitinib/erlotinib and afatinib …

Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study

CE Wu, CF Chang, CY Huang, CT Yang, CHS Kuo… - BMC cancer, 2021 - Springer
… A large cohort study based on the Taiwan Cancer Registry, conducted in 2011–2015,
compared the efficacy of three different TKIs—gefitinib, erlotinib, and afatinin. The results showed …

Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study

G Giaccone, M Gallegos Ruiz, T Le Chevalier… - … Cancer Research, 2006 - AACR
… : Erlotinib has proven activity in pretreated patients with advanced non–small cell lung cancer
(NSCLC). We evaluated erlotinib … Conclusions: Erlotinib shows significant antitumor activity …

[HTML][HTML] Osimertinib in NSCLC with atypical EGFR-activating mutations: A retrospective multicenter study

J Ji, JV Aredo, A Piper-Vallillo, L Huppert… - … Clinical and Research …, 2023 - Elsevier
… , the FLAURA trial compared osimertinib with erlotinib or gefitinib in … More recently, a
retrospective multicenter analysis in … A retrospective study of erlotinib in this setting also revealed …

Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
… with then regularly available TKIs (gefitinib, erlotinib or afatinib). … its retrospective and
non-interventional nature, this studyerlotinib, we observed a poorer adjusted survival for gefitinib

[HTML][HTML] Phase II study of erlotinib as a salvage treatment for non-small-cell lung cancer patients after failure of gefitinib treatment

DH Lee, SW Kim, C Suh, DH Yoon, EJ Yi, JS Lee - Annals of oncology, 2008 - Elsevier
… We conducted a phase II study of erlotinib after failure of gefitinib treatment in patients with …
study who benefited from erlotinib. In our study, of the 15 patients who benefited from gefitinib, …

[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …

PN Ding, SJ Lord, V Gebski, M Links, V Bray… - Journal of Thoracic …, 2017 - Elsevier
trial 4 and this meta-analysis reported similar risks for diarrhea with both erlotinib and gefitinib.
… A retrospective study of the Japanese population reports a risk for pneumonitis of 3.5% …

Erlotinib as salvage treatment after failure to first-line gefitinib in non-small cell lung cancer

MK Wong, AI Lo, B Lam, WK Lam, MS Ip… - Cancer chemotherapy and …, 2010 - Springer
study is to evaluate the efficacy of erlotinib, another EGFR-TKI, after failed first-line use of
gefitinib… Therefore, we conducted a retrospective review of our single institutional experience of …