Cancer combination therapy of the sesquiterpenoid artesunate and the selective EGFR-tyrosine kinase inhibitor erlotinib

T Efferth - Phytomedicine, 2017 - Elsevier
… IC 50 values for artesunate and erlotinib and subsequently subjected to hierarchical cluster
… In conclusion, the combination treatment of artesunate and erlotinib resulted in synergistic …

Erlotinib (Tarceva): an update on the clinical trial program

RS Herbst - Seminars in oncology, 2003 - Elsevier
… with erlotinib are driving the development of the phase III program, and ongoing phase Ib
and II trials are also in progress to evaluate erlotinib as monotherapy or combination therapy in …

Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib combination therapy

A Limsukon, I Susanto, GWS Hoo, SM Dubinett… - Chest, 2009 - Elsevier
… a rational experimental combination regimen. Compared … combination therapy using an
EGFR-tyrosine kinase inhibitor and a COX-2 inhibitor. The rationale for this combination therapy

Combined Therapy with Mutant-Selective EGFR Inhibitor and Met Kinase Inhibitor for Overcoming Erlotinib Resistance in EGFR-Mutant Lung Cancer

T Nakagawa, S Takeuchi, T Yamada, S Nanjo… - Molecular cancer …, 2012 - AACR
… resistance to gefitinib and erlotinib. Our findings suggest that the combination of a Met-TKI
and a mutant-selective EGFR-TKI may be effective in controlling these resistant tumors. …

A review of erlotinib and its clinical use

PA Tang, MS Tsao, MJ Moore - Expert opinion on pharmacotherapy, 2006 - Taylor & Francis
… -based regimens with erlotinib. In the Phase I study of erlotinib in combination with carboplatin
and … Erlotinib combination therapy has been evaluated in metastatic breast cancer with …

[HTML][HTML] Bevacizumab plus erlotinib combination therapy for advanced hereditary leiomyomatosis and renal cell carcinoma-associated renal cell carcinoma: a …

Y Choi, B Keam, M Kim, S Yoon, D Kim… - … : Official Journal of …, 2019 - synapse.koreamed.org
… The combination of bevacizumab plus erlotinib showed promising interim results for HLRCC-…
Based on these results, we analyzed the outcome of bevacizumab plus erlotinib in Korean …

Complete regression of choroidal metastasis secondary to non-small-cell lung cancer with intravitreal bevacizumab and oral erlotinib combination therapy

SW Kim, MJ Kim, K Huh, J Oh - Ophthalmologica, 2009 - karger.com
… and oral erlotinib combination therapy for choroidal … : Combining intravitreal bevacizumab
and oral erlotinib could … , combining intravitreal bevacizumab and oral erlotinib could …

Phase I targeted combination trial of sorafenib and erlotinib in patients with advanced solid tumors

I Duran, SJ Hotte, H Hirte, EX Chen, M MacLean… - Clinical Cancer …, 2007 - AACR
… requiring a dose reduction during the first 28 days of combination therapy, and (d) any
toxicity resulting in a treatment delay of >1 week during the first 28 days of combination therapy. …

Antitumor activity and safety of combination therapy with the Toll-like receptor 9 agonist IMO-2055, erlotinib, and bevacizumab in advanced or metastatic non-small …

DA Smith, P Conkling, DA Richards… - Cancer Immunology …, 2014 - Springer
… High-grade neutropenia and electrolyte disturbances previously reported with TLR9 agonists
combined with platinum-based therapy were not observed in this study. Five of 33 patients …

Erlotinib in cancer treatment

MA Bareschino, C Schettino, T Troiani, E Martinelli… - Annals of oncology, 2007 - Elsevier
… The antitumor activity of erlotinib as single-agent therapy has … Erlotinib is also being evaluated
in combination with … have already failed first line therapy with gemcitabine. The regimen …