… In the cation of the title compound, C 22 H 24 N 3 O 4 + ·Cl − , an active ingredient of the
anticancer drug also known as Tarceva, the quinazoline ring system is planar within 0.044 (3) Å. …

… This study also demonstrated the potent antitumor effects of erlotinib in vivo (5.7-92 mg/kg
po for 20 days starting 4 days posttransplantation) in athymic mice with EGFR-overexpressing …

… Erlotinib (OSI-774) is anticancer drug approved by the United States Food and Drug …
for the estimation of erlotinib hydrochloride in its bulk drug substance and in pharmaceutical …

… Erlotinib hydrochloride (Tarceva; OSI Pharmaceuticals/Genentech/Roche), a member of
a class of targeted anticancer drugs that inhibit the activity of the epidermal growth factor …

… 50 µg/mL of the erlotinib hydrochloride solution three times in … /mL of the erlotinib hydrochloride
drug solution daily for three … 40 µg/mL of erlotinib hydrochloride six times, and the results …

… erlotinib derivatives, and the antitumor activity of the prepared compounds against different
cancer cell lines. Successfully marketed drugs … activity, and drug discovery process could be …

… The solubility of anti-cancer drug, Erlotinib hydrochloride, in supercritical carbon dioxide …
Based on the results, the mole fraction of Erlotinib HCL varied in the range of 1.20 × 10 −6 -2.12 …

… plasma that transport many drugs and compounds. Binding of some drugs to HSA can lead
… We investigated the binding interactions of the Erlotinib Hydrochloride (Erlo) with HSA. Erlo …

… growth signal is a potential target for anticancer treatment. Erlotinib, a 4-anilinoquinazoline, …
The common method for preparation of 4-anilinoquinazolines such as erlotinib involves the …

… for the recrystallization of two anti-cancer APIs, erlotinib HCl and fulvestrant. Erlotinib HCl is
used to … Two anti-cancer active pharmaceutical ingredients erlotinib HCl and fulvestrant were …