Comparison of gefitinib and erlotinib in advanced NSCLC and the effect of EGFR mutations
JY Wu, SG Wu, CH Yang, YL Chang, YC Chang… - Lung cancer, 2011 - Elsevier
… cell lung cancer (NSCLC). This study aimed to compare their clinical uses and the influence
of EGFR mutation. … The usages of erlotinib and gefitinib in advanced NSCLC were analyzed. …
of EGFR mutation. … The usages of erlotinib and gefitinib in advanced NSCLC were analyzed. …
… erlotinib in advanced non-small cell lung cancer (NSCLC) patients (p) with mutations in the tyrosine kinase (TK) domain of the epidermal growth factor receptor (EGFR …
L Paz-Ares, JM Sanchez, A Garcia-Velasco… - Journal of Clinical …, 2006 - ascopubs.org
… and safety of erlotinib in untreated p with advanced NSCLC and mutated EGFR. Methods: …
IIIB-IV chemotherapy-naive p with confirmed NSCLC and mutated EGFR, PS 0–2, age ≥ 18 …
IIIB-IV chemotherapy-naive p with confirmed NSCLC and mutated EGFR, PS 0–2, age ≥ 18 …
A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations
JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
… erlotinib was not significantly superior to gefitinib in advanced NSCLC with EGFR exon 19 or
21 mutations … , upon treatment with erlotinib or gefitinib, patients with exon 19 mutations had …
21 mutations … , upon treatment with erlotinib or gefitinib, patients with exon 19 mutations had …
Erlotinib versus chemotherapy (CT) in advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: Interim …
…, LG Paz-Ares, Spanish Lung Cancer Group - Journal of clinical …, 2011 - ascopubs.org
… NSCLC p with EGFR mutations. Methods: From February 2007 to January 2011, we screened
1,227 p for EGFR mutations, and 174 patients were randomly assigned to receive erlotinib …
1,227 p for EGFR mutations, and 174 patients were randomly assigned to receive erlotinib …
Emerging treatment for advanced lung cancer with EGFR mutation
C Inal, E Yilmaz, B Piperdi, R Perez-Soler… - Expert Opinion on …, 2015 - Taylor & Francis
… Interim results from a Phase I study evaluating the safety and efficacy of nivolumab plus
erlotinib combination in an EGFR-mutant advanced NSCLC cohort, most of whom had …
erlotinib combination in an EGFR-mutant advanced NSCLC cohort, most of whom had …
[HTML][HTML] Nivolumab plus erlotinib in patients with EGFR-mutant advanced NSCLC
S Gettinger, MD Hellmann, LQM Chow… - Journal of Thoracic …, 2018 - Elsevier
… EGFR mutations were included in the trials establishing the use of PD-1 axis inhibitors in
advanced NSCLC. A … erlotinib, bevacizumab, ipilimumab, or platinum-doublet chemotherapy in …
advanced NSCLC. A … erlotinib, bevacizumab, ipilimumab, or platinum-doublet chemotherapy in …
Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians
Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
… erlotinib (150 mg/day, n = 82) to gemcitabine (1000 mg/m 2 , D1,8, every 3 weeks) plus
carboplatin (AUC = 5, n = 72) in advanced NSCLC patients with positive EGFR mutation. Its …
carboplatin (AUC = 5, n = 72) in advanced NSCLC patients with positive EGFR mutation. Its …
… of Central Nervous System Metastases in Patients with Advanced Non–Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib or Erlotinib
S Heon, BY Yeap, GJ Britt, DB Costa, MS Rabin… - Clinical cancer …, 2010 - AACR
… in patients with advanced NSCLC and somatic EGFR mutations initially treated with gefitinib
or erlotinib than published rates of 40% in historical series of advanced NSCLC patients. …
or erlotinib than published rates of 40% in historical series of advanced NSCLC patients. …
Pretreatment EGFR T790M mutation and BRCA1 mRNA expression in erlotinib-treated advanced non–small-cell lung cancer patients with EGFR mutations
R Rosell, MA Molina, C Costa, S Simonetti… - Clinical Cancer …, 2011 - AACR
… Experimental Design: We assessed the T790M mutation in pretreatment diagnostic
specimens from 129 erlotinib-treated advanced NSCLC patients with EGFR mutations. The …
specimens from 129 erlotinib-treated advanced NSCLC patients with EGFR mutations. The …
[HTML][HTML] Pembrolizumab in combination with erlotinib or gefitinib as first-line therapy for advanced NSCLC with sensitizing EGFR mutation
JCH Yang, SM Gadgeel, LVD Sequist, CL Wu… - Journal of Thoracic …, 2019 - Elsevier
… The phase 1 CheckMate 012 study evaluated nivolumab plus erlotinib in patients with
EGFR-mutated advanced NSCLC. One patient was TKI-naive; 20 had received prior erlotinib. The …
EGFR-mutated advanced NSCLC. One patient was TKI-naive; 20 had received prior erlotinib. The …
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